Genomic Location: chr4:1706705...1712306
NR annotation: CAB4013082.1, Fumarate hydratase, mitochondrial [Paramuricea clavata]
Species Muricea muricata · all data for this species · gene families
| CDS |
| BRAKERXEIT00000045843 |
| Transcript |
| BRAKERXEIT00000045843 |
| Protein |
| BRAKERXEIP00000045843.1 |
| UniProt accession | Description |
|---|---|
| P07954 | Fumarate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=FH PE=1 SV=3 |
| Q60HF9 | Fumarate hydratase, mitochondrial OS=Macaca fascicularis OX=9541 GN=FH PE=2 SV=1 |
| P10173 | Fumarate hydratase, mitochondrial OS=Sus scrofa OX=9823 GN=FH PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003293 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF10415 all species → | FumaraseC_C | Fumarase C C-terminus | Domain | Interproscan |
| PF00206 all species → | Lyase_1 | Lyase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR008948 all species → | Homologous_superfamily | L-Aspartase-like | Interproscan |
| IPR000362 all species → | Family | Fumarate lyase family | Interproscan |
| IPR020557 all species → | Conserved_site | Fumarate lyase, conserved site | Interproscan |
| IPR005677 all species → | Family | Fumarate hydratase, class II | Interproscan |
| IPR018951 all species → | Domain | Fumarase C, C-terminal | Interproscan |
| IPR024083 all species → | Homologous_superfamily | Fumarase/histidase, N-terminal | Interproscan |
| IPR022761 all species → | Domain | Fumarate lyase, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11444 all species → | ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0004333 all species → | Molecular Function | fumarate hydratase activity | Interproscan |
| GO:0006106 all species → | Biological Process | fumarate metabolic process | Interproscan |
| GO:0006099 all species → | Biological Process | tricarboxylic acid cycle | Interproscan |
| GO:0016829 all species → | Molecular Function | lyase activity | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0006108 all species → | Biological Process | malate metabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01679 | E4.2.1.2B, fumC, FH; fumarate hydratase, class II | EC:4.2.1.2 | Cushing syndrome | ko04934 | deepkoala |
Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
