Gene detail

Detailed information of BRAKERXEIP00000046407.1 in Muricea muricata

Genomic Location: chr4:3149301...3164626
NR annotation: XP_028409802.1, neutral alpha-glucosidase AB-like isoform X2 [Dendronephthya gigantea]
Species Muricea muricata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

BRAKERXEIT00000046407

ATGGCTGATGGTgaaaaatattcaattgcttttgtTACCATCAATGATAAAGAGGCTGCTGCAAAGTTGTCTGATGAGATGCTTGACAAGAAATTAGTTGCATGTGTAAATATTGTTTCTGGAGTGGAATCTAGgtATGTATGGGAAGGTAAAGTAAACATTGACAGTGAGGTTTTAATGaTAATCAAGACAAGAACATCTCGAATAAAGGAGCTGGGTGAATTAATCAATCCTTCATTGGCAATAGACATGTCAAAGTTCAAGAAATGTGAAGACAGCAGTTTTTGCAAgcGAAACAGGGCCATTCCACTTGGCGAAAGCCCATATTCAATTGTTCCTGGTTCAATACAGTTCTCAGATTCTATCATAGATGTACAAATTTTGAATAATAAAACAAATGTAGTCCTTAGTCTTCAAGTAATCATATTGCAACATAATACAGTTAGgtttaaaattaatgaaattaatcCAATCCACCAACGTTATGAAGTTCAAGATGTTTTAGTGGGCGAACCTACTCATTCAAGTTATGAAAAAGTTAGCGAGAGTGATCATCAAGTTCATGTCAAGTTTAACAACAATGGTTTGATCATAACAAAGAAGCCATTACGCTTGGACTTTCTTGTTGATAATCAAATTGCTGTCTCAGTGAACTCCAAAGGATTAATGAATTTTGAGCATTACCAAGCCAAGAAACCCAACTCGGAAAAGAAGGCGGAAGACCCTGAACCAACTATTGCTGTGGATGAAAACAGCGAAGAAGAGCCCAAAGATGAGGAAGAAAATGTTGAGGAAGATTCAAAAGACGAAGAGCCAAAACCAGTCGAAGAAGAGTCGTGGGAGGAATCATTTCACGAACATAAAGATTCCAGACCTAAAGGACCATCGTCTGTTGGTCTGGATATCTCTTTTCTTGGCTTTGATAATGTCTACGGTATTCCTGAACACGCTGATTCCCTGGCACTCAAATCGACCATGGGCAAAGAACCGTATCGACTTTTCAATCTGGACGTATTTGAGTACGATTTGAACAATGGCATGGCTTTATACGGATCTATTCCCTACATGTTGGCACACAGCATGAACAAAACTGTCGGAGTATTTTGGTTGAATGCCGCTGAAACATGGATTGATATCAGCACGGAGGATGCTAAGAAGAACATGTTGGACTCACTAATGTCTTTCTTCAGCGTGGAGGAGAATTCGCAGCAGATTGACACACACTGGATGTCAGAAAGTGGGATTATCGACGTATTTGTGATGTTAGGCCCCAAGCCTCACGATGTATTTAAGCAATACGCCGCACTAACCGGCCCTGCGACCTTGCCCCCGGTATTTGCTATTGCTTATCACCAGTGCCGCTGGAACTACAACGATCAAGACGATGTTATCACTGTTGATGCTAACTTTGACAAACATGACATTCCATATGACGTTTTGTGGCTGGATATTGAACACACAGATGGAAAGCGGTACATGACATGGGATTCTCACAAGTTTCCAAACCCAGAAGAAATGCAAAACAAGTTGGCCGCTAAAGGAAGAAGAATGGTGACGATCGTGGATCCGCATATTAAAAGGGATGACGATTATCATATTCACAGGGAAGCAAGTTCCAAAGGTTACTACGTGAAAAACAAGGACGGCGCTGACTATGAAGGATGGTGTTGGCCAGGTTCATCGTCCTGGATTGATTTCTTCAATCCGGTCGTGAGGGATTGGTGGGCGAGTAAGTTTGCTCTTGATCAGTACAAGGGCTCCACTCCAACCCTGAGCGTTTGGAACGATATGAACGAGGTTTCCGTGTTCAATGGCCCCGAGATCACCATGCATAAGGACGCCGTACACTATGGCGGGTGGGAAAACCGCGATGTTCACAATCTCTacggtttttacaatcaaatgtCCACGTACTATGGTTTGAAACGAAGATCTGGCGACAAGGAACGACCGTTTGTCTTATCCAGGGCTTTCTTTGCAGGAACACAGAGATATGGAGCAATATGGACAGGGGATAATATAGCGGAATGGTCACATTTGAAAATGTCCTTGCCAATGATCTTGACACTGGGAGTAACTGGAATGCAGTTTAGTGGAGCCGATGTTGGTGGATTCTTCAAGAATCCTGATGGCGAACTTCTCGTGCGATGGTATCAGGCTGGGGCCTATCTCCCCTTTTTCCGCGCGCATGCTCACCTGGACACGAAGCGCCGTGAGCCGTGGTTGTTTGAAGACAGATACAAGAACCTGATGCGGGAAGCGATACGGCATCGTTATGCATTGCTGCCGTTCTGGTACACGCTGTTTCATGAGGCATCTCGATCTGGTTCGCCTATTGTAACACCACTGTGGGTCGAGTATCCCGAGGACAAATCAACCTTTACCATGGAAGATCAATACTTGCTAGGTCGTGATCTCTTAGTGAAGCCAGTAACAACACAAGGCCAAGCCACACTTGATGTGTATCTTCCTGACAAGGACGGGTTGTGGTACGATTTATCTGGCAACAAGTTCCATCTTGGTGGTCAAACTATTCACGTTGCTACACCGCTTAATATGATTCCAGTCTTTCAACGGGGTGGAAGTGTAATTCCTCGAAAAGAACGAATTCGACGTTGTTCATCTCTCATGACTGAGGATCCTTATACTCTGGTTGTGGCGCTTAGTAAAAAGGGCGAGGCGGAAGGCAAAGTCTATTTAGATGATGGAATAAGTTTCGATTATGAGAATGGAAAGTATGAGTATCGCGAAATTACATTTAAACAAGGAAAACTAGAATCGAGATCACTGGACAGTTCGTCTCATTATGAAACAAAGTCCTGGCTGGAACGCATTGTCATAATGGGGATGAGTCAAAATCCATCGCAGATCATTGTGACTGATAAAGATGGAAAGACAAGAAAACTGGATTACCAACACGACTTGGCTGCCTACCGACTGACCATTAAGAAACCTGCCGTGAACATGTCGGAGGACTGGAGCATAGTCTTGTACGCGTAA

Transcript

BRAKERXEIT00000046407

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8BHN3	Neutral alpha-glucosidase AB OS=Mus musculus OX=10090 GN=Ganab PE=1 SV=1
Q14697	Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3
Q4R4N7	Neutral alpha-glucosidase AB OS=Macaca fascicularis OX=9541 GN=GANAB PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002887 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13802 all species →	Gal_mutarotas_2	Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain	Domain	Interproscan
PF01055 all species →	Glyco_hydro_31_2nd	Glycosyl hydrolases family 31 TIM-barrel domain	Domain	Interproscan
PF17137 all species →	DUF5110	Domain of unknown function (DUF5110)	Family	Interproscan
PF21365 all species →	Glyco_hydro_31_3rd	Glycosyl hydrolase family 31 C-terminal domain	Domain	Interproscan
PF03091 all species →	CutA1	CutA1 divalent ion tolerance protein	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011013 all species →	Homologous_superfamily	Galactose mutarotase-like domain superfamily	Interproscan
IPR013780 all species →	Homologous_superfamily	Glycosyl hydrolase, all-beta	Interproscan
IPR025887 all species →	Domain	Glycoside hydrolase family 31, N-terminal domain	Interproscan
IPR017853 all species →	Homologous_superfamily	Glycoside hydrolase superfamily	Interproscan
IPR015867 all species →	Homologous_superfamily	Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal	Interproscan
IPR000322 all species →	Domain	Glycoside hydrolase family 31, TIM barrel domain	Interproscan
IPR033403 all species →	Domain	Domain of unknown function DUF5110	Interproscan
IPR048395 all species →	Domain	Glycosyl hydrolase family 31, C-terminal domain	Interproscan
IPR011322 all species →	Homologous_superfamily	Nitrogen regulatory PII-like, alpha/beta	Interproscan
IPR004323 all species →	Family	Divalent ion tolerance protein, CutA	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22762 all species →	ALPHA-GLUCOSIDASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0030246 all species →	Molecular Function	carbohydrate binding	Interproscan
GO:0004553 all species →	Molecular Function	hydrolase activity, hydrolyzing O-glycosyl compounds	Interproscan
GO:0006491 all species →	Biological Process	N-glycan processing	Interproscan
GO:0090599 all species →	Molecular Function	alpha-glucosidase activity	Interproscan
GO:0010038 all species →	Biological Process	response to metal ion	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05546	GANAB; mannosyl-oligosaccharide alpha-1,3-glucosidase	EC:3.2.1.207	Protein processing in endoplasmic reticulum	ko04141	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →