Genomic Location: chr9:1557121...1565315
NR annotation: XP_028413127.1, crossover junction endonuclease EME1-like [Dendronephthya gigantea]
Species Muricea muricata · all data for this species · gene families
| CDS |
| BRAKERXEIT00000053596 |
| Transcript |
| BRAKERXEIT00000053596 |
| Protein |
| BRAKERXEIP00000053596.1 |
| UniProt accession | Description |
|---|---|
| Q8BJW7 | Structure-specific endonuclease subunit EME1 OS=Mus musculus OX=10090 GN=Eme1 PE=1 SV=1 |
| Q5NVA9 | Structure-specific endonuclease subunit EME1 OS=Pongo abelii OX=9601 GN=EME1 PE=3 SV=1 |
| Q96AY2 | Structure-specific endonuclease subunit EME1 OS=Homo sapiens OX=9606 GN=EME1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004649 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02732 all species → | ERCC4 | ERCC4 domain | Domain | Interproscan |
| PF21292 all species → | EME1-MUS81_C | EME1/MUS81, C-terminal | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006166 all species → | Domain | ERCC4 domain | Interproscan |
| IPR042530 all species → | Homologous_superfamily | EME1/EME2, C-terminal domain | Interproscan |
| IPR003892 all species → | Domain | Ubiquitin system component CUE | Interproscan |
| IPR033310 all species → | Family | Mms4/EME1/EME2 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21077 all species → | EME1 PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0004518 all species → | Molecular Function | nuclease activity | Interproscan |
| GO:0043130 all species → | Molecular Function | ubiquitin binding | Interproscan |
| GO:0000712 all species → | Biological Process | resolution of meiotic recombination intermediates | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| GO:0006302 all species → | Biological Process | double-strand break repair | Interproscan |
| GO:0008821 all species → | Molecular Function | crossover junction DNA endonuclease activity | Interproscan |
| GO:0031297 all species → | Biological Process | replication fork processing | Interproscan |
| GO:0031573 all species → | Biological Process | mitotic intra-S DNA damage checkpoint signaling | Interproscan |
| GO:0048476 all species → | Cellular Component | Holliday junction resolvase complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10882 | EME1, MMS4; crossover junction endonuclease EME1 | EC:3.1.22.- | DNA repair and recombination proteins | ko03400 | deepkoala |
Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
