Detailed information of BRAKERYMEP00000007248.1 in Astreopora myriophthalma

Genomic Location: BLFK01000192.1:489469...501800
NR annotation: XP_044174437.1, folylpolyglutamate synthase, mitochondrial-like isoform X1 [Acropora millepora]
Species Astreopora myriophthalma · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q924L9Folylpolyglutamate synthase, mitochondrial OS=Cricetulus griseus OX=10029 GN=FPGS PE=2 SV=1
A6H751Folylpolyglutamate synthase, mitochondrial OS=Bos taurus OX=9913 GN=FPGS PE=2 SV=1
Q05932Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=FPGS PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002708 (this species only) · gene tree & orthology

 Pfam domain
No Pfam domain signature was recorded for BRAKERYMEP00000007248.1 in Astreopora myriophthalma.
 InterPro
InterPro termTypeDescriptionSource
IPR018109
all species →
Conserved_siteFolylpolyglutamate synthetase, conserved siteInterproscan
IPR001645
all species →
FamilyFolylpolyglutamate synthetaseInterproscan
IPR036565
all species →
Homologous_superfamilyMur-like, catalytic domain superfamilyInterproscan
IPR023600
all species →
FamilyFolylpolyglutamate synthase, eukaryotaInterproscan
IPR036615
all species →
Homologous_superfamilyMur ligase, C-terminal domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11136
all species →
FOLYLPOLYGLUTAMATE SYNTHASE-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004326
all species →
Molecular Functiontetrahydrofolylpolyglutamate synthase activityInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0009396
all species →
Biological Processfolic acid-containing compound biosynthetic processInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0005739
all species →
Cellular ComponentmitochondrionInterproscan
GO:0005829
all species →
Cellular ComponentcytosolInterproscan
GO:0046901
all species →
Biological Processtetrahydrofolylpolyglutamate biosynthetic processInterproscan
GO:0009058
all species →
Biological Processbiosynthetic processInterproscan
GO:0016881
all species →
Molecular Functionacid-amino acid ligase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01930FPGS; folylpolyglutamate synthaseEC:6.3.2.17
Antifolate resistanceko01523deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Astreopora myriophthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Astreopora myriophthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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