Gene detail

Detailed information of BRAKERYMEP00000028380.1 in Astreopora myriophthalma

Genomic Location: BLFK01000837.1:114161...124467
NR annotation: XP_029185339.2, LOW QUALITY PROTEIN: putative Polycomb group protein ASXL2 [Acropora millepora]
Species Astreopora myriophthalma · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

BRAKERYMET00000028380

ATGAGCGCGGAAAAAGTtgaaacgaagaagaaaaaggGTTTGACATGGGCTGAAGCGGCGAAACAGGTGCTCGAGAGATCTGTAGATCCTCTGACCCACAAAGACATCCTAAAGGTTATACAAGACGAAGGTTTACGCGATTTAAGtcgCGGTAATGCACCACTTGCATGTTTGAATGCAATGCTTCATCACCACTCCCGAGGTCCAAACGATCTGTTTATAAAGGTTGAGGGGCGAATGAGCTGTTACAGACTCAATCCAAATAGAGTGGAGAGCACAGGAGAAAACTCCACACAAGACTCTGATTCTGACCTGTCAAGTATTCCTGATGACACTGAATTTAACCATTTCTTGGACAAGGATAGTTTAAATGGCCGACACCTGAGTAATGGAAAAGTCAAGATGCCCCTGGGAACCAAAGACATTGTGATGCCACAACTTAAACCACCACCGCCCAATCCATTCCCCAGGGACCCTAAGCCAAAGCCCTCACTTACCAAAGATGGTAGACTGCAGAAGAAACGTGGGCCCAAACCTGGACCACGTAGCTCGTCTTCAAACAAGAGACCAAGGTTGACTAGTACAAGACCTGTCCCAAAGGTGGTGTTAAAAAATCTCAAAGTTGGTACAGTTGAAAGTGCTACTGGATCAAATGGCAAAGATGGTAGTACTAAGGTTAAGTCTCCACCTGTCCTTGTTGAACCTTCATCCAAACTCATCCCACCGTCAAGTGCATCAGTAGCAGCTAATGCCATAGCTGATCACAGTTTTTCAAGGCTTCCAGGTTCTGCTAATGATGTTGACGGTAAAGAAAAGCTTGAGAAGTTTTCTGACCTTTGGACAAATTCGAAGCCGCGAAGATACAAGAAAATGAGTGTTGCTGCCCAGTTGAAGAGAACGAAAGAAGGCCGGATAGATATTTCAACACCAGATTCTATTCTAACAAGTATTCCTCTTCGCtctctCATAAGTCAGCGGACATTTAACATGCTTCCAGCTCTGTATCAATACCAGCTTGTTACTTTGTTGCCAAAAGTCGACAGGTCCAGGGGCAATGACGGTGGCCTGAGACCATCGCATACTGCTTTTACCAATGAGTTCTTTGCCAGTGCGTGTCATTCATGGAAGGATCGGCTTCAAGATGgtGATTTCATGACAGACatgcaacaaaaaatgaaacaggAAGAGGAGAGGCTGGCCAAGCTGGATCCTTGGAAGGCAAACTTCTTTGAACCTGTCTGGGGCAAAAGgaAACTTTCGGAATCTGATTCCTCGTCCCTAGATCCCGCGCATGCGTATTTTACTGCACCTCTTTCACCGGCCCCCGCCGTATCGCCTAGAAGCGCACTGCCATCGAGTCACAAAGATCCCAGTCAGTACACTCCAACAAAATCACCCCGGCTGAGCGACGGTATAATGCAGCCCCTAGCGGTCACGGTTCCCCTCAAGAAACTCCCGTCTCACTGTCTCCCCAAACGGGTGTCTGAATCAAGGAGATCAGAGGCCGCCAAACAGCTGAGGGTTAACTCCAACGCACGGCCTTCACGGCCGCGGTCTATTCCTATATTTCGGATGGTTACAGTAGCTGTCGCCACAGAGGCGCTGAAAGCCGTTAGAACTTGTGCACCTGATAATATGCTCACGGCCAGTACGGTATACTCCAGAAAAAGAACTATAAAAATTCCAGGCAGTGAAACGGCCTCGGATGGCTCTGTAACTAAAGAATCATCTATGTCAAATGCATCTATACTCAATAATGACGCTGTGGATCTGCGGGCACCCGCTACACTTATAAAAGAGAGACCGCCATCTAGGGCCGCCATGCAAAAGCAGGCAGCTAACAGAGAGAACTTGACGCGTCGGCCAACCTCGGGTAGCGACGCAAAGGGCTTTGCAGCCAACACTGTCACTTCCAAAAGCTTCAACAGGTCTTTGTTGCTCAAGAGTTGCTCGTGTCGGTTAAAGGCTATGGAAGTCTGCAGAAAGTGTGGTGCCTTCTGTCACGATGATTGTATCAGTACTGCGCAGCTCTGCAGCGCATGCGTCAACTAA

Transcript

BRAKERYMET00000028380

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P59598	Polycomb group protein ASXL1 OS=Mus musculus OX=10090 GN=Asxl1 PE=1 SV=1
Q8IXJ9	Polycomb group protein ASXL1 OS=Homo sapiens OX=9606 GN=ASXL1 PE=1 SV=4
Q76L83	Putative Polycomb group protein ASXL2 OS=Homo sapiens OX=9606 GN=ASXL2 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005292 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13919 all species →	ASXH	Asx homology domain	Domain	Interproscan
PF05066 all species →	HARE-HTH	HB1, ASXL, restriction endonuclease HTH domain	Family	Interproscan
PF13922 all species →	PHD_3	PHD domain of transcriptional enhancer, Asx	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR028020 all species →	Domain	ASX, DEUBAD domain	Interproscan
IPR007759 all species →	Domain	ASXL, HARE-HTH domain	Interproscan
IPR044867 all species →	Domain	DEUBAD domain	Interproscan
IPR024811 all species →	Family	Polycomb protein ASX/ASX-like	Interproscan
IPR026905 all species →	Domain	Protein ASX-like, PHD domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13578 all species →	ADDITIONAL SEX COMBS LIKE PROTEIN ASXL	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006355 all species →	Biological Process	regulation of DNA-templated transcription	Interproscan
GO:0003682 all species →	Molecular Function	chromatin binding	Interproscan
GO:0009887 all species →	Biological Process	animal organ morphogenesis	Interproscan
GO:0035517 all species →	Cellular Component	PR-DUB complex	Interproscan
GO:0045944 all species →	Biological Process	positive regulation of transcription by RNA polymerase II	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11471	ASXL; additional sex combs-like protein	-	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Astreopora myriophthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Astreopora myriophthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →