Gene detail

Detailed information of BRAKERYMEP00000028609.1 in Astreopora myriophthalma

Genomic Location: BLFK01000843.1:1088078...1099433
NR annotation: XP_029207376.2, LOW QUALITY PROTEIN: pyruvate carboxylase, mitochondrial-like [Acropora millepora]
Species Astreopora myriophthalma · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

BRAKERYMET00000028609

ATGCTGCGTGCACATGCCTCACGcttcaataaaataatacagcaACAGTTTGCCTCCAGCAGTAGAATATGGTCGACATGTCGTTTTATCCATGCTGGAAACAAGAACTGTTCAAGCAACAAGCCTGAGCCACAGAGAACTGAAATAAAGAAGATTCTAGTTGCAAATCGTGGAGAAATTGCCATTAGAGTTTTCCGTGCTGCTGCTGAAGCTGGAATTGAGACAGTTGCCATCTACTCAGAACAAGATGCAAATCTTATGCACAGACAAAAAGCTGATGAAGCATACCTTATTGGCAAAGGAATGCCACCAGTAGCTGCCTATTTAAATATTCCTGAGATCATCAAAATAGCCAAGGACACAGATACTGATGCAATCCACCCAGGATATGGATTTCTCTCAGAAAGAGCAAACTTTGCGGAGGCTTGTGTCAAGAGTGGCATCATTTTCATTGGCCCTTCTCCATCAATTGTGAAGCTTATGGGTGACAAAGTTGAAGCACGGAAAGTTGCAATAAATGCTGGTATTCCTGTGGTTCCTGGTACAGAGACACCCATAAGAACTGCAGCGGAAGCCAGAGCTTTCTGTGAAGAGCATGGGCTTCCTGTAATTACCAAGGCAGCATACGGTGGTGGTGGGCGTGGCATGAGGGTTATTCATAAAATAGATGATGTTGAAGAGTACTTCAACTTGGCCAGTAATGAAGCTTTTGCAGCCTTTGGTGATGGTTCGATGTTTATTGAGAGGTTTGTTGCAAAACCAAGGCACATTGAAGTACAAGTTGTGGGAGATGCTTATGGAAATGTGGTGCACCTTTATGAACGTGACTGTTCAGTACAGAGGCGTCACCAGAAGATTGTTGAAATTGCACCAGCTCCACATTTAGATACTAAAATCAGGGACAAGATGACAAGCGATGCCATTACCCTGTGTGAGGCAGTTGGATACCAGAATGCGGGCACTGTGGAATTCCTCTTGGATCCAGAGGGTAATCATTACTTCATGGAGGTGAATGCAAGACTGCAAGTGGAACACACAGTGACAGAGGAAATTACGGGTGTTGATTTGGTGAGAACGCAAATTGGTGTTGCCGAAGGAAAGTCATTAGAGGAACTAGGACTTCATCAAGATGATATCAAAGTGACAGGTTCAGCAATTCAAGCACGAATAACAACTGAAGACCCTGCTAATGACTTCACCCCTGATACTGGCCGAATTGAGGTTTTTCGCACAGGAGAGGGTATGGGAATTCGTTTGGATGGAAGTTCGATGTTCCCAGGTGCTGTGATCTCTCCTCATTACGATTCACTGCTGACAAAAGTAATAAGTCATGGCTCAACTCACAGAGATGCAGCAAATAAACTTCTGAGGGCTCTGCGGGAATTCCGAGTCAGAGGTGTGAAGACCAACATTCCTTTCCTGATGAATGTTCTCCAAGAAGAGGAATTCCTTGGAGGTGCTGTAGCAACAGATTTTATTCTAAACAGACCAGAGCTGTTGAAAGTGGAGCGAGGTCAAAATCGTGCTCAGAAACTGCTTCAGTACCTTGGAAATGTGATGGTTAATGGCCCATGTACGCCGCTGGCGACTGGGCTGAAGCCATCCAAGGCTGTTCCTGAAGCCCCGGAGGTGCCCAAAACATCAAGCACTAGCAATGGGTGTTATCTGAGACCAAGTGGCTTGCGTGATATATTACTTCAGCAAGGACCAGAAGGATTTGCCAGACATGTGCGCAATTGCCATCGTCTTCTTCTGACAGATACAACATTCAGAGATGCACATCAATCGCTACTGGCCACCAGAGTACGCACGCATGACATGCTCAAAGTGGCGCCTTTCGTGTCGCATTACTTTGCAAATGCTTTTAGTTTGGAGTGTTGGGGAGGTGCAACGTTTGACGTTGCTCTGCGCTTTCTGTACGAGTGTCCCTGGGAGAGACTGGCGCTGCTGCGTGAAGCAGTACCCAACATTCCGTTCCAGATGCTGCTGAGAGGTGCTAATGCCGTGGGATACACCAGTTACCCTGATAATGTGGTCTTTAAATTCTGCAATAAAGCTCATGAGATGGGAATGGATATCTTTCGTGTGTTTGATTCTCTGAATTACCTCCCTAACTTACAGCTTGGTATTGAAGCCTCTGGGCAGGCTGGCGGAGTTGTGGAAGCAGCCATATCATACACTGGCGATGTATTCAACCCAAAGAACACGAAATACAACATCGACTACTACATGAACCTAGCTACTGATCTGGTGAGAGCTGGCATTCACGTGCTCTGCATCAAGGATATGGCTGGGGTATTGAGGCCCAATGCTGCCACGCTGTTGATAGGTTCGCTTCGTGCTCAGTTTCCCAAGTTGCCTATTCACGTGCATACACATGACACAGCTGGAGCAGGTGTGGCATCCATGCTGGCCGCGTCGGAGGCTGGGGCGGATGTGGTGGATGTGGCAGTGGACTCTTTGTCTGGAATGACGTCACAGCCCAGTATGGGCGCCATCGTTGCTGCTCTGGAAAACACCGATAAAGAAACGGGAATTCCAATCGAACGAGTTCATCAGTACAGCGAATACTGGGAACTAGCTCGTCAGCTATACGCGCCATTTGAAAGCACGGTGACCATGAAGACAGGAAATGCCGATGTGTACGAGAACGAGATTCCGGGGGGACAGTACACCAATCTACACTTCCAAGCTTACTCCCTTGGGCTGGCTGATCAGTTCACAGAAGTCAAGAAAAAGTACACCATGGCGAACAAACTCCTGGGAGATATAGTCAAGGTGACACCCACATCCAAAGTTGTGGGAGACTTGGCTCAGTTTATGGTGCAGAATAAATTGGATGATCGTGACGTTCTCCTCAAGGCGGGTGATCTTGATTTCCCATCATCAGTTGTGGAATTTATGCAGGGTTACCTCGGACAACCCCATGGGGGATTCCCAGAACCACTTAGAACCAAGATTTTGAAGGGACGTCTTATCATTGATGGGAGACCGGGTGAATCTTTGGAGCCACTTGACTTTGATGCGCTGAAGGCGAAGTTGCAGGAAGATTTTGGAGAAAATGCCATCAAGGATGAAGATGTTCTCAGTGGTGCCTTGTACCCCAAAGTATTCAGAGATTACATGCTGTTTAGAGAGGAGTATGGTCCTGTTAATGGACTACCTACCAGGCTTTTTTTCACCGGCCCGGAGATAGGTGAGGAATTCCAAGTGGAGATTCAGCCAGGAAAAGTTTTGAACATCAAGGTGCTTGCCATTAGTGATCTGCACCCCAATGGACAAAGGGAAGTGTTCTGTGAGATGAATGGACAACTTAGGACTGTCATGGTAGAGGATAAATCTGTCACTAAGACACTGGAACGACACCCTAAAGCGGACAAGTCAGTCAGGGGTTCAGTGGGAGCTCCCATGCCAGGGAAAGTAGTTGGCATCCGCGTCAAGGAGAAGGAGGTAGTCAAGAAGGGTTCGCCTTTGGTGGTGTTGAGTGCCATGAAGATGGAGACTAATGTCAGTGCGCCCATTGATGGGACGATCACCAAGATCTCGGTCGCCTTGAACCAGAGCTTGGAGGCTGGAGATCTGCTGGTTGATATTGAACCACTCAGTTAA

Transcript

BRAKERYMET00000028609

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q29RK2	Pyruvate carboxylase, mitochondrial OS=Bos taurus OX=9913 GN=PC PE=2 SV=2
Q05920	Pyruvate carboxylase, mitochondrial OS=Mus musculus OX=10090 GN=Pc PE=1 SV=1
P11498	Pyruvate carboxylase, mitochondrial OS=Homo sapiens OX=9606 GN=PC PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003376 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00682 all species →	HMGL-like	HMGL-like	Domain	Interproscan
PF00289 all species →	Biotin_carb_N	Biotin carboxylase, N-terminal domain	Domain	Interproscan
PF02785 all species →	Biotin_carb_C	Biotin carboxylase C-terminal domain	Domain	Interproscan
PF02786 all species →	CPSase_L_D2	Carbamoyl-phosphate synthase L chain, ATP binding domain	Domain	Interproscan
PF02436 all species →	PYC_OADA	Conserved carboxylase domain	Domain	Interproscan
PF00364 all species →	Biotin_lipoyl	Biotin-requiring enzyme	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000891 all species →	Domain	Pyruvate carboxyltransferase	Interproscan
IPR013785 all species →	Homologous_superfamily	Aldolase-type TIM barrel	Interproscan
IPR011054 all species →	Homologous_superfamily	Rudiment single hybrid motif	Interproscan
IPR011761 all species →	Domain	ATP-grasp fold	Interproscan
IPR000089 all species →	Domain	Biotin/lipoyl attachment	Interproscan
IPR005482 all species →	Domain	Biotin carboxylase, C-terminal	Interproscan
IPR005479 all species →	Domain	Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain	Interproscan
IPR011764 all species →	Domain	Biotin carboxylation domain	Interproscan
IPR005930 all species →	Family	Pyruvate carboxylase	Interproscan
IPR005481 all species →	Domain	Biotin carboxylase-like, N-terminal domain	Interproscan
IPR016185 all species →	Homologous_superfamily	Pre-ATP-grasp domain superfamily	Interproscan
IPR003379 all species →	Domain	Carboxylase, conserved domain	Interproscan
IPR011053 all species →	Homologous_superfamily	Single hybrid motif	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43778 all species →	PYRUVATE CARBOXYLASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0004736 all species →	Molecular Function	pyruvate carboxylase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006090 all species →	Biological Process	pyruvate metabolic process	Interproscan
GO:0006094 all species →	Biological Process	gluconeogenesis	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01958	PC, pyc; pyruvate carboxylase	EC:6.4.1.1	Carbon fixation pathways in prokaryotes	ko00720	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Astreopora myriophthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Astreopora myriophthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →