Detailed information of BRAKERYMEP00000036849.1 in Astreopora myriophthalma

Genomic Location: BLFK01001094.1:1369887...1377673
NR annotation: XP_044184919.1, dual specificity mitogen-activated protein kinase kinase 6-like [Acropora millepora]
Species Astreopora myriophthalma · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P52564Dual specificity mitogen-activated protein kinase kinase 6 OS=Homo sapiens OX=9606 GN=MAP2K6 PE=1 SV=1
P70236Dual specificity mitogen-activated protein kinase kinase 6 OS=Mus musculus OX=10090 GN=Map2k6 PE=1 SV=1
Q5E9X2Dual specificity mitogen-activated protein kinase kinase 6 OS=Bos taurus OX=9913 GN=MAP2K6 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001218 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00069
all species →
PkinaseProtein kinase domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000719
all species →
DomainProtein kinase domainInterproscan
IPR011009
all species →
Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan
IPR008271
all species →
Active_siteSerine/threonine-protein kinase, active siteInterproscan
IPR017441
all species →
Binding_siteProtein kinase, ATP binding siteInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR48013
all species →
DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000165
all species →
Biological ProcessMAPK cascadeInterproscan
GO:0004708
all species →
Molecular FunctionMAP kinase kinase activityInterproscan
GO:0004672
all species →
Molecular Functionprotein kinase activityInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0006468
all species →
Biological Processprotein phosphorylationInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K04432MAP2K3, MKK3; mitogen-activated protein kinase kinase 3EC:2.7.12.2
Protein kinasesko01001deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Astreopora myriophthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Astreopora myriophthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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