Gene detail

Detailed information of CAB3976621.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB3976621.1, serine threonine- kinase mTOR [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

Sequence

No sequence record for CAB3976621.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P42345	Serine/threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1
P42346	Serine/threonine-protein kinase mTOR OS=Rattus norvegicus OX=10116 GN=Mtor PE=1 SV=1
Q9JLN9	Serine/threonine-protein kinase mTOR OS=Mus musculus OX=10090 GN=Mtor PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003121 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02259 all species →	FAT	FAT domain	Repeat	Interproscan
PF02260 all species →	FATC	FATC domain	Family	Interproscan
PF11865 all species →	DUF3385	Domain of unknown function (DUF3385)	Repeat	Interproscan
PF00454 all species →	PI3_PI4_kinase	Phosphatidylinositol 3- and 4-kinase	Family	Interproscan
PF08771 all species →	FRB_dom	FKBP12-rapamycin binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR018936 all species →	Conserved_site	Phosphatidylinositol 3/4-kinase, conserved site	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR003151 all species →	Domain	PIK-related kinase, FAT	Interproscan
IPR003152 all species →	Domain	FATC domain	Interproscan
IPR011990 all species →	Homologous_superfamily	Tetratricopeptide-like helical domain superfamily	Interproscan
IPR000403 all species →	Domain	Phosphatidylinositol 3-/4-kinase, catalytic domain	Interproscan
IPR050517 all species →	Family	DNA Damage Response and Repair Kinase	Interproscan
IPR036738 all species →	Homologous_superfamily	FKBP12-rapamycin binding domain superfamily	Interproscan
IPR014009 all species →	Domain	PIK-related kinase	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR024585 all species →	Domain	Serine/threonine-protein kinase mTOR domain	Interproscan
IPR026683 all species →	Domain	Serine/threonine-protein kinase TOR, catalytic domain	Interproscan
IPR036940 all species →	Homologous_superfamily	Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily	Interproscan
IPR009076 all species →	Domain	FKBP12-rapamycin binding domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11139 all species →	ATAXIA TELANGIECTASIA MUTATED ATM -RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016301 all species →	Molecular Function	kinase activity	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0016242 all species →	Biological Process	negative regulation of macroautophagy	Interproscan
GO:0031929 all species →	Biological Process	TOR signaling	Interproscan
GO:0031931 all species →	Cellular Component	TORC1 complex	Interproscan
GO:0031932 all species →	Cellular Component	TORC2 complex	Interproscan
GO:0044877 all species →	Molecular Function	protein-containing complex binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K07203	MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR	EC:2.7.11.1	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB3976621.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples

12TPM > 0

4Conditions

16.2Max TPM

5.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
apical branchlet · Control at T25	6	5	7.57	15.32
apical branchlet · Temperature treatment at T0	6	3	5.92	16.15
apical branchlet · Temperature treatment at T25	5	3	6.46	13.59
apical branchlet · Control at T0	4	1	1.43	5.74

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR19977440	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	15.32
SRR19977444	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	15.31
SRR19977441	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	9.25
SRR19977455	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	2.80
SRR19977433	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	2.72
SRR19977439	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.00
SRR19977427	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	16.15
SRR19977428	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	12.19
SRR19977438	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	7.19
SRR19977426	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977436	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977437	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977432	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	13.59
SRR19977425	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	10.86
SRR19977435	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	7.84
SRR19977434	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977463	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977443	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	5.74
SRR19977442	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00
SRR19977445	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00
SRR19977446	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.