Genomic Location: not available for this species
NR annotation: CAB3977525.1, C-1-tetrahydrofolate synthase, cytoplasmic [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families
CAB3977525.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| P11586 | C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4 |
| Q922D8 | C-1-tetrahydrofolate synthase, cytoplasmic OS=Mus musculus OX=10090 GN=Mthfd1 PE=1 SV=4 |
| P27653 | C-1-tetrahydrofolate synthase, cytoplasmic OS=Rattus norvegicus OX=10116 GN=Mthfd1 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001689 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00763 all species → | THF_DHG_CYH | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain | Domain | Interproscan |
| PF02882 all species → | THF_DHG_CYH_C | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain | Domain | Interproscan |
| PF01268 all species → | FTHFS | Formate--tetrahydrofolate ligase | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR020630 all species → | Domain | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain | Interproscan |
| IPR020631 all species → | Domain | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain | Interproscan |
| IPR000672 all species → | Family | Tetrahydrofolate dehydrogenase/cyclohydrolase | Interproscan |
| IPR020867 all species → | Conserved_site | Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR000559 all species → | Family | Formate-tetrahydrofolate ligase, FTHFS | Interproscan |
| IPR020628 all species → | Conserved_site | Formate-tetrahydrofolate ligase, FTHFS, conserved site | Interproscan |
| IPR046346 all species → | Homologous_superfamily | Aminoacid dehydrogenase-like, N-terminal domain superfamily | Interproscan |
| IPR036291 all species → | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR48099 all species → | C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004488 all species → | Molecular Function | methylenetetrahydrofolate dehydrogenase (NADP+) activity | Interproscan |
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0004329 all species → | Molecular Function | formate-tetrahydrofolate ligase activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0004477 all species → | Molecular Function | methenyltetrahydrofolate cyclohydrolase activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0035999 all species → | Biological Process | tetrahydrofolate interconversion | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00288 | MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase | EC:1.5.1.5 EC:3.5.4.9 EC:6.3.4.3 | Exosome | ko04147 | deepkoala |
Transcript abundance of CAB3977525.1 across 21 RNA-seq samples of Paramuricea clavata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| apical branchlet · Control at T25 | 6 | 0 | 0.00 | 0.00 | |
| apical branchlet · Temperature treatment at T0 | 6 | 0 | 0.00 | 0.00 | |
| apical branchlet · Temperature treatment at T25 | 5 | 0 | 0.00 | 0.00 | |
| apical branchlet · Control at T0 | 4 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM,
StringTie quantification over 21 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
