Gene detail

Detailed information of CAB3978327.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB3978327.1, cytoplasmic dynein 2 heavy chain 1-like [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

Sequence

No sequence record for CAB3978327.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q27802	Cytoplasmic dynein 2 heavy chain 1 OS=Tripneustes gratilla OX=7673 GN=DYH1B PE=2 SV=2
Q45VK7	Cytoplasmic dynein 2 heavy chain 1 OS=Mus musculus OX=10090 GN=Dync2h1 PE=1 SV=1
Q9JJ79	Cytoplasmic dynein 2 heavy chain 1 OS=Rattus norvegicus OX=10116 GN=Dync2h1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002117 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF12780 all species →	AAA_8	P-loop containing dynein motor region D4	Domain	Interproscan
PF12774 all species →	AAA_6	Hydrolytic ATP binding site of dynein motor region	Domain	Interproscan
PF21264 all species →	DYNC2H1_AAA_dom	Cytoplasmic dynein 2 heavy chain 1, AAA+ ATPase domain	Domain	Interproscan
PF18198 all species →	AAA_lid_11	Dynein heavy chain AAA lid domain	Domain	Interproscan
PF12777 all species →	MT	Microtubule-binding stalk of dynein motor	Domain	Interproscan
PF08393 all species →	DHC_N2	Dynein heavy chain, N-terminal region 2	Family	Interproscan
PF18199 all species →	Dynein_C	Dynein heavy chain C-terminal domain	Domain	Interproscan
PF12781 all species →	AAA_9	ATP-binding dynein motor region	Domain	Interproscan
PF12775 all species →	AAA_7	P-loop containing dynein motor region	Domain	Interproscan
PF03028 all species →	Dynein_heavy	Dynein heavy chain region D6 P-loop domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR043160 all species →	Homologous_superfamily	Dynein heavy chain, C-terminal domain, barrel region	Interproscan
IPR024317 all species →	Domain	Dynein heavy chain, AAA module D4	Interproscan
IPR035699 all species →	Domain	Dynein heavy chain, hydrolytic ATP-binding dynein motor region	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR049400 all species →	Domain	Cytoplasmic dynein 2 heavy chain 1, AAA+ ATPase domain	Interproscan
IPR003593 all species →	Domain	AAA+ ATPase domain	Interproscan
IPR041658 all species →	Domain	Dynein heavy chain AAA lid domain	Interproscan
IPR024743 all species →	Domain	Dynein heavy chain, coiled coil stalk	Interproscan
IPR026983 all species →	Family	Dynein heavy chain	Interproscan
IPR043157 all species →	Homologous_superfamily	Dynein heavy chain, AAA1 domain, small subdomain	Interproscan
IPR013602 all species →	Domain	Dynein heavy chain, linker	Interproscan
IPR041228 all species →	Domain	Dynein heavy chain, C-terminal domain	Interproscan
IPR035706 all species →	Domain	Dynein heavy chain, ATP-binding dynein motor region	Interproscan
IPR042219 all species →	Homologous_superfamily	Dynein heavy chain AAA lid domain superfamily	Interproscan
IPR042222 all species →	Homologous_superfamily	Dynein heavy chain, domain 2, N-terminal	Interproscan
IPR004273 all species →	Domain	Dynein heavy chain region D6 P-loop domain	Interproscan
IPR042228 all species →	Homologous_superfamily	Dynein heavy chain, linker, subdomain 3	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45703 all species →	DYNEIN HEAVY CHAIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0007018 all species →	Biological Process	microtubule-based movement	Interproscan
GO:0030286 all species →	Cellular Component	dynein complex	Interproscan
GO:0045505 all species →	Molecular Function	dynein intermediate chain binding	Interproscan
GO:0051959 all species →	Molecular Function	dynein light intermediate chain binding	Interproscan
GO:0008569 all species →	Molecular Function	minus-end-directed microtubule motor activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10414	DYNC2H, DNCH2; dynein cytoplasmic 2 heavy chain	-	Cytoskeleton proteins	ko04812	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB3978327.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples

14TPM > 0

4Conditions

5.5Max TPM

1.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
apical branchlet · Control at T25	6	5	3.38	5.50
apical branchlet · Temperature treatment at T0	6	5	2.03	3.66
apical branchlet · Temperature treatment at T25	5	2	0.47	1.30
apical branchlet · Control at T0	4	2	1.33	3.48

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR19977444	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	5.50
SRR19977441	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	4.96
SRR19977455	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	4.78
SRR19977440	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	2.84
SRR19977439	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	2.19
SRR19977433	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.00
SRR19977427	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	3.66
SRR19977428	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	3.42
SRR19977437	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	1.88
SRR19977438	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	1.63
SRR19977436	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	1.56
SRR19977426	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977425	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	1.30
SRR19977435	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	1.05
SRR19977432	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977434	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977463	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977443	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	3.48
SRR19977446	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	1.85
SRR19977442	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00
SRR19977445	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.