Detailed information of CAB3981957.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB3981958.1, collagen alpha-1(IV) chain [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

 Sequence
No sequence record for CAB3981957.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P27393Collagen alpha-2(IV) chain OS=Ascaris suum OX=6253 PE=2 SV=1
P29400Collagen alpha-5(IV) chain OS=Homo sapiens OX=9606 GN=COL4A5 PE=1 SV=2
Q28247Collagen alpha-5(IV) chain OS=Canis lupus familiaris OX=9615 GN=COL4A5 PE=2 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001701 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01391
all species →
CollagenCollagen triple helix repeat (20 copies)RepeatInterproscan
PF01413
all species →
C4C-terminal tandem repeated domain in type 4 procollagenDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR016187
all species →
Homologous_superfamilyC-type lectin foldInterproscan
IPR050149
all species →
FamilyCollagen superfamilyInterproscan
IPR008160
all species →
RepeatCollagen triple helix repeatInterproscan
IPR001442
all species →
DomainCollagen IV, non-collagenousInterproscan
IPR036954
all species →
Homologous_superfamilyCollagen IV, non-collagenous domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR24023
all species →
COLLAGEN ALPHAInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005615
all species →
Cellular Componentextracellular spaceInterproscan
GO:0030020
all species →
Molecular Functionextracellular matrix structural constituent conferring tensile strengthInterproscan
GO:0030198
all species →
Biological Processextracellular matrix organizationInterproscan
GO:0031012
all species →
Cellular Componentextracellular matrixInterproscan
GO:0062023
all species →
Cellular Componentcollagen-containing extracellular matrixInterproscan
GO:0005201
all species →
Molecular Functionextracellular matrix structural constituentInterproscan
GO:0005581
all species →
Cellular Componentcollagen trimerInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K06237COL4A; collagen type IV alpha-Glycosaminoglycan binding proteinsko00536deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB3981957.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
20TPM > 0
4Conditions
340.9Max TPM
109.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
apical branchlet · Control at T25 6 6 110.70 200.31
apical branchlet · Temperature treatment at T0 6 6 112.82 234.52
apical branchlet · Temperature treatment at T25 5 5 142.33 340.90
apical branchlet · Control at T0 4 3 59.06 144.21

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR19977441 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 200.31
SRR19977440 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 150.92
SRR19977439 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 86.98
SRR19977455 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 85.39
SRR19977444 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 75.25
SRR19977433 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 65.38
SRR19977427 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 234.52
SRR19977428 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 127.59
SRR19977437 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 116.54
SRR19977436 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 88.68
SRR19977438 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 83.12
SRR19977426 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 26.44
SRR19977434 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 340.90
SRR19977435 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 136.19
SRR19977425 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 122.06
SRR19977432 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 83.94
SRR19977463 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 28.55
SRR19977443 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 144.21
SRR19977445 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 60.92
SRR19977442 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 31.09
SRR19977446 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated24CAB3996786.10.906050441471385
Negatively correlated6CAB3984165.1-0.598288993808889

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.not in the sequence tableopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.not in the sequence tableopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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