Gene detail

Detailed information of CAB3985968.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB3985968.1, Methylmalonyl- mutase, mitochondrial [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

Sequence

No sequence record for CAB3985968.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9GK13	Methylmalonyl-CoA mutase, mitochondrial OS=Bos taurus OX=9913 GN=MMUT PE=2 SV=1
P16332	Methylmalonyl-CoA mutase, mitochondrial OS=Mus musculus OX=10090 GN=Mmut PE=1 SV=2
P22033	Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004409 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02310 all species →	B12-binding	B12 binding domain	Domain	Interproscan
PF01642 all species →	MM_CoA_mutase	Methylmalonyl-CoA mutase	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR006158 all species →	Domain	Cobalamin (vitamin B12)-binding domain	Interproscan
IPR016176 all species →	Homologous_superfamily	Cobalamin (vitamin B12)-dependent enzyme, catalytic	Interproscan
IPR036724 all species →	Homologous_superfamily	Cobalamin-binding domain superfamily	Interproscan
IPR006098 all species →	Domain	Methylmalonyl-CoA mutase, alpha chain, catalytic	Interproscan
IPR006099 all species →	Domain	Methylmalonyl-CoA mutase, alpha/beta chain, catalytic	Interproscan
IPR006159 all species →	Domain	Methylmalonyl-CoA mutase, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR48101 all species →	METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0031419 all species →	Molecular Function	cobalamin binding	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0004494 all species →	Molecular Function	methylmalonyl-CoA mutase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0019678 all species →	Biological Process	propionate metabolic process, methylmalonyl pathway	Interproscan
GO:0016866 all species →	Molecular Function	intramolecular transferase activity	Interproscan
GO:0016853 all species →	Molecular Function	isomerase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01847	MUT; methylmalonyl-CoA mutase	EC:5.4.99.2	Cobalamin transport and metabolism	ko04980	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB3985968.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples

17TPM > 0

4Conditions

51.0Max TPM

10.2Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
apical branchlet · Control at T25	6	6	13.84	20.09
apical branchlet · Temperature treatment at T0	6	4	7.34	19.52
apical branchlet · Temperature treatment at T25	5	4	12.89	50.98
apical branchlet · Control at T0	4	3	5.70	12.95

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR19977444	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	20.09
SRR19977439	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	19.43
SRR19977440	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	17.68
SRR19977441	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	16.33
SRR19977455	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	9.43
SRR19977433	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.06
SRR19977436	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	19.52
SRR19977427	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	9.98
SRR19977428	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	7.55
SRR19977438	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	6.97
SRR19977426	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977437	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977434	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	50.98
SRR19977435	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	10.41
SRR19977432	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	1.96
SRR19977425	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	1.09
SRR19977463	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977443	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	12.95
SRR19977445	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	7.35
SRR19977442	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	2.49
SRR19977446	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.