Gene detail

Detailed information of CAB3986480.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB3986480.1, dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial- [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

Sequence

No sequence record for CAB3986480.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q19749	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Caenorhabditis elegans OX=6239 GN=dlat-1 PE=1 SV=1
Q8BMF4	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dlat PE=1 SV=2
P08461	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Rattus norvegicus OX=10116 GN=Dlat PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001913 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02817 all species →	E3_binding	e3 binding domain	Family	Interproscan
PF00198 all species →	2-oxoacid_dh	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	Domain	Interproscan
PF00364 all species →	Biotin_lipoyl	Biotin-requiring enzyme	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR004167 all species →	Domain	Peripheral subunit-binding domain	Interproscan
IPR001078 all species →	Domain	2-oxoacid dehydrogenase acyltransferase, catalytic domain	Interproscan
IPR011053 all species →	Homologous_superfamily	Single hybrid motif	Interproscan
IPR036625 all species →	Homologous_superfamily	E3-binding domain superfamily	Interproscan
IPR006257 all species →	Family	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex	Interproscan
IPR000089 all species →	Domain	Biotin/lipoyl attachment	Interproscan
IPR023213 all species →	Homologous_superfamily	Chloramphenicol acetyltransferase-like domain superfamily	Interproscan
IPR045257 all species →	Family	Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component	Interproscan
IPR003016 all species →	Binding_site	2-oxo acid dehydrogenase, lipoyl-binding site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23151 all species →	DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016746 all species →	Molecular Function	acyltransferase activity	Interproscan
GO:0004742 all species →	Molecular Function	dihydrolipoyllysine-residue acetyltransferase activity	Interproscan
GO:0006090 all species →	Biological Process	pyruvate metabolic process	Interproscan
GO:0045254 all species →	Cellular Component	pyruvate dehydrogenase complex	Interproscan
GO:0005967 all species →	Cellular Component	obsolete mitochondrial pyruvate dehydrogenase complex	Interproscan
GO:0006086 all species →	Biological Process	acetyl-CoA biosynthetic process from pyruvate	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00627	DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase)	EC:2.3.1.12	Lipoic acid metabolism	ko00785	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB3986480.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples

15TPM > 0

4Conditions

119.2Max TPM

27.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
apical branchlet · Control at T25	6	5	37.28	77.98
apical branchlet · Temperature treatment at T0	6	5	40.08	119.21
apical branchlet · Temperature treatment at T25	5	3	13.86	44.60
apical branchlet · Control at T0	4	2	9.83	26.13

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR19977444	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	77.98
SRR19977441	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	49.76
SRR19977455	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	48.62
SRR19977439	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	27.18
SRR19977440	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	20.15
SRR19977433	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.00
SRR19977428	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	119.21
SRR19977426	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	48.35
SRR19977436	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	48.34
SRR19977427	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	16.82
SRR19977438	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	7.75
SRR19977437	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977463	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	44.60
SRR19977435	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	12.90
SRR19977432	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	11.80
SRR19977425	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977434	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977445	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	26.13
SRR19977443	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	13.19
SRR19977442	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00
SRR19977446	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.