Detailed information of CAB3987606.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB3987606.1, CCR4-NOT transcription complex subunit 1 isoform X5 [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

 Sequence
No sequence record for CAB3987606.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
A5YKK6CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2
A0JP85CCR4-NOT transcription complex subunit 1 OS=Xenopus tropicalis OX=8364 GN=cnot1 PE=2 SV=1
A1A5H6CCR4-NOT transcription complex subunit 1 OS=Danio rerio OX=7955 GN=cnot1 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002467 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF04054
all species →
Not1CCR4-Not complex component, Not1RepeatInterproscan
PF16417
all species →
CNOT1_TTP_bindCCR4-NOT transcription complex subunit 1 TTP binding domainRepeatInterproscan
PF12842
all species →
DUF3819CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819DomainInterproscan
PF16418
all species →
CNOT1_HEATCCR4-NOT transcription complex subunit 1 HEAT repeatDomainInterproscan
PF16415
all species →
CNOT1_CAF1_bindCCR4-NOT transcription complex subunit 1 CAF1-binding domainRepeatInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR007196
all species →
DomainCCR4-Not complex component, Not1, C-terminalInterproscan
IPR032193
all species →
DomainCCR4-NOT transcription complex subunit 1, TTP binding domainInterproscan
IPR038535
all species →
Homologous_superfamilyCCR4-NOT subunit 1, TTP binding domain superfamilyInterproscan
IPR024557
all species →
DomainCCR4-NOT transcription complex subunit 1, domain 4Interproscan
IPR032194
all species →
DomainCCR4-NOT transcription complex subunit 1, HEAT repeatInterproscan
IPR032191
all species →
DomainCCR4-NOT transcription complex subunit 1, CAF1-binding domainInterproscan
IPR040398
all species →
FamilyCCR4-NOT transcription complex subunit 1Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR13162
all species →
CCR4-NOT TRANSCRIPTION COMPLEXInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000288
all species →
Biological Processnuclear-transcribed mRNA catabolic process, deadenylation-dependent decayInterproscan
GO:0000932
all species →
Cellular ComponentP-bodyInterproscan
GO:0017148
all species →
Biological Processnegative regulation of translationInterproscan
GO:0030015
all species →
Cellular ComponentCCR4-NOT core complexInterproscan
GO:0060090
all species →
Molecular Functionmolecular adaptor activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K12604CNOT1, NOT1; CCR4-NOT transcription complex subunit 1-Messenger RNA biogenesisko03019deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB3987606.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
21TPM > 0
4Conditions
44.5Max TPM
19.1Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
apical branchlet · Control at T25 6 6 25.23 44.48
apical branchlet · Temperature treatment at T0 6 6 17.03 30.83
apical branchlet · Temperature treatment at T25 5 5 18.04 29.06
apical branchlet · Control at T0 4 4 14.54 22.67

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR19977444 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 44.48
SRR19977441 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 36.24
SRR19977455 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 30.99
SRR19977440 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 19.86
SRR19977433 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 12.68
SRR19977439 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 7.15
SRR19977428 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 30.83
SRR19977426 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 27.15
SRR19977427 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 24.62
SRR19977438 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 12.95
SRR19977437 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 4.40
SRR19977436 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 2.21
SRR19977463 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 29.06
SRR19977435 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 19.69
SRR19977434 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 17.28
SRR19977425 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 13.17
SRR19977432 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 11.00
SRR19977443 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 22.67
SRR19977446 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 17.83
SRR19977445 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 14.93
SRR19977442 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 2.72

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated12CAB3984833.10.930359007450314
Negatively correlated46CAB4037663.1-0.670805816417479

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.not in the sequence tableopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.not in the sequence tableopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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