Gene detail

Detailed information of CAB3990251.1 in Paramuricea clavata

Genomic Location: :...
NR annotation: CAB3990251.1, delta-1-pyrroline-5-carboxylate synthase isoform X1 [Paramuricea clavata]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q5R4M8	Delta-1-pyrroline-5-carboxylate synthase OS=Pongo abelii OX=9601 GN=ALDH18A1 PE=2 SV=1
P54886	Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2
Q9Z110	Delta-1-pyrroline-5-carboxylate synthase OS=Mus musculus OX=10090 GN=Aldh18a1 PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00171	Aldedh	Aldehyde dehydrogenase family	Family	Interproscan
PF00696	AA_kinase	Amino acid kinase family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR005766	Family	Delta l-pyrroline-5-carboxylate synthetase	Interproscan
IPR016163	Homologous_superfamily	Aldehyde dehydrogenase, C-terminal	Interproscan
IPR001057	Family	Glutamate/acetylglutamate kinase	Interproscan
IPR036393	Homologous_superfamily	Acetylglutamate kinase-like superfamily	Interproscan
IPR019797	Conserved_site	Glutamate 5-kinase, conserved site	Interproscan
IPR020593	Conserved_site	Gamma-glutamyl phosphate reductase GPR, conserved site	Interproscan
IPR016162	Homologous_superfamily	Aldehyde dehydrogenase, N-terminal	Interproscan
IPR015590	Domain	Aldehyde dehydrogenase domain	Interproscan
IPR000965	Domain	GPR domain	Interproscan
IPR001048	Domain	Aspartate/glutamate/uridylate kinase	Interproscan
IPR016161	Homologous_superfamily	Aldehyde/histidinol dehydrogenase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11063	GLUTAMATE SEMIALDEHYDE DEHYDROGENASE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0003824	Molecular Function	catalytic activity	Interproscan
GO:0006561	Biological Process	proline biosynthetic process	Interproscan
GO:0016620	Molecular Function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Interproscan
GO:0005524	Molecular Function	ATP binding	Interproscan
GO:0016301	Molecular Function	kinase activity	Interproscan
GO:0004349	Molecular Function	glutamate 5-kinase activity	Interproscan
GO:0004350	Molecular Function	glutamate-5-semialdehyde dehydrogenase activity	Interproscan
GO:0016491	Molecular Function	oxidoreductase activity	Interproscan
GO:0005739	Cellular Component	mitochondrion	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K12657	ALDH18A1, P5CS; delta-1-pyrroline-5-carboxylate synthetase	EC:2.7.2.11 EC:1.2.1.41	Arginine and proline metabolism	ko00330	deepkoala