Gene detail

Detailed information of CAB3991031.1 in Paramuricea clavata

Genomic Location: pcla8_s001807:36533...39022
NR annotation: CAB3991031.1, beta-hexosaminidase subunit beta-like [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-PACLA_8A054736

CGCTTGGTCTGATATTTCGCAAAGGTCATATGATTTCGCTTGACACCGGAAGATGATATGGTCATAGCATAGTTAGTCACACCACGGTGGTCACACACTGTGCTAATCTCGTGATTGCTATTGTTGAGCAACATTCGCTGAACTACTGCTATCGAAGCAAATCATGGCAGTTATCATGAGAAATTTCGTGGTTTTATGTGCTTTCATACTTGGTTGTAAAGCTGCCGAAGTACCGCAACAGTGCAATCCTTCGGGCCCTTCCTCGCCGCACGGAAATGCCGTGAACTCGGGCAGACAGAATGTGCATTTAGGCCCTGATGGTTATGTAAGTGGTTCTATCTGGCCCAAACCACAACAACATACTGTTGGCGAAGAAACATTCTCGTTAAGTCCAGACACATTTAAATTCACATCAACAGGCGAGGCAAGTGATGTTTTAACGGCTGCAATGGCAAGGTATCGTGGTCTTACATTTCCTGACATGATTCACTCGAATGTGCTCAGATTTCGCCGTGATCTATCTGCGCTAACGTCCTTGGAAATTACAGTGAAGGAAAAGTATGCACCTATGACATTTGAAAGTGATGAATCATACGCACTAGCAGTGAGTGCTCCAGCATCAAGTTTAACTGCGAACACAGTTTGGGGAGCTTTGCGAGGACTTGAAACATTTAGTCAACTTGTATACCAAGATGAACATGACAATTACCTGGCTCGAGAAGGCAAAATTACTGACTTCCCTCGTTTTCATTACCGCGGTTTTCTTATCGATACATCCAGACATTTTATAGATGTCAGTGTGATATTACGTCATATTGATGCATTGGCATAtgctaagtataatattttgcaCTGGCATATTGTTGATGATCAATCATTTCCATTTGTCAGTAAAACATTTCCCTCACTTAGTAATGTCGGTGCTTATAACAACGTCACGCATATTTATGACATAGATGATGTGGCTACAGTTATTGAGTATGGTCGAATGCGTGGTATTCGTGTAGTACCTGAGTTTGACACACCGGGACACACGCAGTCATGGGTCAGCATCAAAGATCTTCTTACACCATGTTATTCTGGTGGAAAACCAACTGGAACTTATGGTCCTATCAACCCCACATTAAATTCCACTTACACCTTCCTTAAATCATTCTTCGGAGAAATAGGCACGCGTTTCCTCGATGACTACATTCACTTGGGCGGAGATGAAGTGTCGTTCAGTTGCTGGGAGAGCAATCCTAATGTACTGGCTTGGATGGACAAAATGGGATTTGGCAAGAATTTCTCACTTCTTGAACAATATTATGAACAAAAGTTAATTGATATTGTAGGTGGTTTGAAGAAGAAATATATCATTTGGCAAGAAGTGATTGATAATCAAGTGACTGTCAATCCTGATACTGTGGTTAATGTTTGGAAAGGTGGTTGGCAAAATGAAATGGCTAAAGTTACAGCAAAGAACTTGAACGTTGTACTTTCTTCACCATGGTACTTGAATTACATTTCATATGGTAATGATTGGCCAAAATATTATAGTGTTGAACCGACTGCATTTAATGGAACAAGTGCACAGAAGAAGCTTGTACTTGGTGGAACAACGTGTATGTGGGGTGAGTGGGTGGATGGGACAAACCTTCTCCCAAGAAGCTGGCCAAGATCCTTAGCTATCTCTGAAAGATTGTGGAGTTCCATCAACACGACTGACGTAGCAGATGCGCAAGGTCGTCTCAGAGAGCATCGATGTCGTTACTTGATGCGTGGTATTCCAGCACAAAATGGTGTTCAGTCAAAGTATTGTCGATATGAGTGGACATTGTGAACTGATCTTTGACTTATAACCCTTACTTTTAATTGAGAAGAATAACATTGATTGTAACAAATAtgataaataaattctttggGATTCTTTGGTGGAGTTATAGAATAGAATATGTTAATgaaagaaaaaataaatatttagtaTATTTTGACATTCTAAAGTGATATTTCTGAATTTCGTATTCTGTTTTGAAAAGGCTGAAATTTAACGTAAATGAAGGGTTCGaatatattgtaaaaatatCTCAAATCATTCCATTTActttttaatttatgtaatatttcaaatccgactatgagggcTGGACTAGATTTCACGTCTTTGCAATTTCATCAACTGTCCTAcgcgaagccgaggactggatcataatgtgaggacttgaaatctagtcagtccgaattggaggatttgaaatgacatctgcAGACGAATAATAAAttactacttaaagtgaggtgaattaattttgatccagtacAAAGacggaattaattttgatccagtcctaggactggatcaacaTACTTCACCAtgcaggtatccagtattattatcatgtgagcaaaataaagcaatatggttggctaatttactcataaattattaatgagttctttatacagggtgtctaaaaaaaacgctatggaaattcaacaggctgtcgtgca

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P49614	Beta-hexosaminidase subunit beta OS=Felis catus OX=9685 GN=HEXB PE=2 SV=2
P07686	Beta-hexosaminidase subunit beta OS=Homo sapiens OX=9606 GN=HEXB PE=1 SV=4
P20060	Beta-hexosaminidase subunit beta OS=Mus musculus OX=10090 GN=Hexb PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001007 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF14845 all species →	Glycohydro_20b2	beta-acetyl hexosaminidase like	Domain	Interproscan
PF00728 all species →	Glyco_hydro_20	Glycosyl hydrolase family 20, catalytic domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR025705 all species →	Family	Beta-hexosaminidase	Interproscan
IPR029018 all species →	Homologous_superfamily	Beta-hexosaminidase-like, domain 2	Interproscan
IPR029019 all species →	Domain	Beta-hexosaminidase, eukaryotic type, N-terminal	Interproscan
IPR015883 all species →	Domain	Glycoside hydrolase family 20, catalytic domain	Interproscan
IPR017853 all species →	Homologous_superfamily	Glycoside hydrolase superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22600 all species →	BETA-HEXOSAMINIDASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004563 all species →	Molecular Function	beta-N-acetylhexosaminidase activity	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0005764 all species →	Cellular Component	lysosome	Interproscan
GO:0006689 all species →	Biological Process	ganglioside catabolic process	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0030203 all species →	Biological Process	glycosaminoglycan metabolic process	Interproscan
GO:0004553 all species →	Molecular Function	hydrolase activity, hydrolyzing O-glycosyl compounds	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12373	HEXA_B; hexosaminidase	EC:3.2.1.52	Chaperones and folding catalysts	ko03110	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB3991031.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples

19TPM > 0

4Conditions

56.9Max TPM

29.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
apical branchlet · Control at T25	6	6	40.94	56.86
apical branchlet · Temperature treatment at T0	6	6	30.65	52.49
apical branchlet · Temperature treatment at T25	5	3	11.80	34.05
apical branchlet · Control at T0	4	4	30.20	56.62

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR19977439	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	56.86
SRR19977455	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	54.55
SRR19977441	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	54.34
SRR19977444	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	44.62
SRR19977440	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	22.26
SRR19977433	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	13.02
SRR19977427	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	52.49
SRR19977428	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	35.26
SRR19977436	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	28.92
SRR19977426	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	28.70
SRR19977438	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	25.06
SRR19977437	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	13.49
SRR19977435	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	34.05
SRR19977432	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	15.38
SRR19977425	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	9.55
SRR19977434	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977463	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977443	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	56.62
SRR19977445	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	34.64
SRR19977446	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	16.32
SRR19977442	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	13.22

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.