Genomic Location: not available for this species
NR annotation: CAB3991230.1, folylpolyglutamate synthase, mitochondrial-like isoform X1, partial [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families
CAB3991230.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q05932 | Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=FPGS PE=1 SV=3 |
| A6H751 | Folylpolyglutamate synthase, mitochondrial OS=Bos taurus OX=9913 GN=FPGS PE=2 SV=1 |
| P48760 | Folylpolyglutamate synthase, mitochondrial OS=Mus musculus OX=10090 GN=Fpgs PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002827 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02875 all species → | Mur_ligase_C | Mur ligase family, glutamate ligase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004101 all species → | Domain | Mur ligase, C-terminal | Interproscan |
| IPR001645 all species → | Family | Folylpolyglutamate synthetase | Interproscan |
| IPR018109 all species → | Conserved_site | Folylpolyglutamate synthetase, conserved site | Interproscan |
| IPR036615 all species → | Homologous_superfamily | Mur ligase, C-terminal domain superfamily | Interproscan |
| IPR036565 all species → | Homologous_superfamily | Mur-like, catalytic domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11136 all species → | FOLYLPOLYGLUTAMATE SYNTHASE-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0009058 all species → | Biological Process | biosynthetic process | Interproscan |
| GO:0016881 all species → | Molecular Function | acid-amino acid ligase activity | Interproscan |
| GO:0004326 all species → | Molecular Function | tetrahydrofolylpolyglutamate synthase activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0009396 all species → | Biological Process | folic acid-containing compound biosynthetic process | Interproscan |
| GO:0046901 all species → | Biological Process | tetrahydrofolylpolyglutamate biosynthetic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01930 | FPGS; folylpolyglutamate synthase | EC:6.3.2.17 | Antifolate resistance | ko01523 | deepkoala |
Transcript abundance of CAB3991230.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| apical branchlet · Control at T25 | 6 | 4 | 7.22 | 13.06 | |
| apical branchlet · Temperature treatment at T0 | 6 | 3 | 2.69 | 6.76 | |
| apical branchlet · Temperature treatment at T25 | 5 | 3 | 9.59 | 28.33 | |
| apical branchlet · Control at T0 | 4 | 1 | 1.93 | 7.74 |
Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM,
StringTie quantification over 21 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
