Gene detail

Detailed information of CAB3993274.1 in Paramuricea clavata

Genomic Location: :...
NR annotation: CAB3993274.1, serine threonine- kinase endoribonuclease IRE1 [Paramuricea clavata]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
O75460	Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Homo sapiens OX=9606 GN=ERN1 PE=1 SV=2
Q9EQY0	Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Mus musculus OX=10090 GN=Ern1 PE=1 SV=1
P32361	Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=IRE1 PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF06479	Ribonuc_2-5A	Ribonuclease 2-5A	Family	Interproscan
PF00069	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR010513	Domain	KEN domain	Interproscan
IPR038357	Homologous_superfamily	KEN domain superfamily	Interproscan
IPR008271	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR045133	Family	Serine/threonine-protein kinase/endoribonuclease IRE1/2-like	Interproscan
IPR000719	Domain	Protein kinase domain	Interproscan
IPR011009	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13954	IRE1-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004540	Molecular Function	RNA nuclease activity	Interproscan
GO:0006397	Biological Process	mRNA processing	Interproscan
GO:0004672	Molecular Function	protein kinase activity	Interproscan
GO:0006468	Biological Process	protein phosphorylation	Interproscan
GO:0004521	Molecular Function	RNA endonuclease activity	Interproscan
GO:0004674	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0030968	Biological Process	endoplasmic reticulum unfolded protein response	Interproscan
GO:0036498	Biological Process	IRE1-mediated unfolded protein response	Interproscan
GO:0051082	Molecular Function	unfolded protein binding	Interproscan
GO:0070059	Biological Process	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Interproscan
GO:1990604	Cellular Component	IRE1-TRAF2-ASK1 complex	Interproscan
GO:0005524	Molecular Function	ATP binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K08852	ERN1; serine/threonine-protein kinase/endoribonuclease IRE1	EC:2.7.11.1 EC:3.1.26.-	Protein kinases	ko01001	deepkoala