Gene detail

Detailed information of CAB3996286.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB3996286.1, sestrin-1 isoform X1 [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

Sequence

No sequence record for CAB3996286.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P58003	Sestrin-1 OS=Xenopus laevis OX=8355 GN=sesn1 PE=2 SV=1
Q9Y6P5	Sestrin-1 OS=Homo sapiens OX=9606 GN=SESN1 PE=1 SV=2
Q4R6P7	Sestrin-1 OS=Macaca fascicularis OX=9541 GN=SESN1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006469 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF04636 all species →	PA26	PA26 p53-induced protein (sestrin)	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR029052 all species →	Homologous_superfamily	Metallo-dependent phosphatase-like	Interproscan
IPR029032 all species →	Homologous_superfamily	AhpD-like	Interproscan
IPR006730 all species →	Family	Sestrin	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12474 all species →	P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:1901031 all species →	Biological Process	regulation of response to reactive oxygen species	Interproscan
GO:0016239 all species →	Biological Process	positive regulation of macroautophagy	Interproscan
GO:0016684 all species →	Molecular Function	oxidoreductase activity, acting on peroxide as acceptor	Interproscan
GO:0070728 all species →	Molecular Function	L-leucine binding	Interproscan
GO:0071233 all species →	Biological Process	cellular response to L-leucine	Interproscan
GO:1904262 all species →	Biological Process	negative regulation of TORC1 signaling	Interproscan
GO:1990253 all species →	Biological Process	cellular response to leucine starvation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10141	SESN1_3; sestrin 1/3	-	Longevity regulating pathway	ko04211	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB3996286.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples

14TPM > 0

4Conditions

49.8Max TPM

6.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
apical branchlet · Control at T25	6	4	8.13	44.87
apical branchlet · Temperature treatment at T0	6	4	3.94	23.03
apical branchlet · Temperature treatment at T25	5	4	12.72	49.80
apical branchlet · Control at T0	4	2	2.15	6.42

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR19977444	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	44.87
SRR19977441	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	2.89
SRR19977455	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.76
SRR19977440	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.28
SRR19977433	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.00
SRR19977439	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.00
SRR19977428	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	23.03
SRR19977427	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.28
SRR19977438	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.17
SRR19977437	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.16
SRR19977426	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977436	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977434	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	49.80
SRR19977435	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	11.09
SRR19977425	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	1.87
SRR19977432	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.82
SRR19977463	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977443	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	6.42
SRR19977446	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	2.16
SRR19977442	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00
SRR19977445	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.