Genomic Location: not available for this species
NR annotation: CAB3999162.1, molybdenum cofactor biosynthesis 1 isoform X1 [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families
CAB3999162.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q5RKZ7 | Molybdenum cofactor biosynthesis protein 1 OS=Mus musculus OX=10090 GN=Mocs1 PE=1 SV=2 |
| Q1JQD7 | Molybdenum cofactor biosynthesis protein 1 OS=Bos taurus OX=9913 GN=MOCS1 PE=2 SV=2 |
| Q9NZB8 | Molybdenum cofactor biosynthesis protein 1 OS=Homo sapiens OX=9606 GN=MOCS1 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001789 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06463 all species → | Mob_synth_C | Molybdenum Cofactor Synthesis C | Domain | Interproscan |
| PF01967 all species → | MoaC | MoaC family | Family | Interproscan |
| PF04055 all species → | Radical_SAM | Radical SAM superfamily | Domain | Interproscan |
| PF13353 all species → | Fer4_12 | 4Fe-4S single cluster domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR010505 all species → | Domain | Molybdenum cofactor biosynthesis protein A-like, twitch domain | Interproscan |
| IPR013483 all species → | Family | Molybdenum cofactor biosynthesis protein A | Interproscan |
| IPR023045 all species → | Family | Molybdenum cofactor biosynthesis C | Interproscan |
| IPR036522 all species → | Homologous_superfamily | Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily | Interproscan |
| IPR002820 all species → | Domain | Molybdopterin cofactor biosynthesis C (MoaC) domain | Interproscan |
| IPR006638 all species → | Domain | Elp3/MiaA/NifB-like, radical SAM core domain | Interproscan |
| IPR047594 all species → | Family | Molybdenum cofactor biosynthesis C, bacteria/eukaryotes | Interproscan |
| IPR007197 all species → | Domain | Radical SAM | Interproscan |
| IPR000385 all species → | Conserved_site | MoaA/NifB/PqqE, iron-sulphur binding, conserved site | Interproscan |
| IPR013785 all species → | Homologous_superfamily | Aldolase-type TIM barrel | Interproscan |
| IPR050105 all species → | Family | Molybdenum cofactor biosynthesis MoaA/MoaC | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22960 all species → | MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006777 all species → | Biological Process | Mo-molybdopterin cofactor biosynthetic process | Interproscan |
| GO:0019008 all species → | Cellular Component | obsolete molybdopterin synthase complex | Interproscan |
| GO:0051539 all species → | Molecular Function | 4 iron, 4 sulfur cluster binding | Interproscan |
| GO:0046872 all species → | Molecular Function | metal ion binding | Interproscan |
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0051536 all species → | Molecular Function | iron-sulfur cluster binding | Interproscan |
| GO:0061798 all species → | Molecular Function | GTP 3',8'-cyclase activity | Interproscan |
| GO:0061799 all species → | Molecular Function | cyclic pyranopterin monophosphate synthase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K20967 | MOCS1; GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase | EC:4.1.99.22 EC:4.6.1.17 | Folate biosynthesis | ko00790 | deepkoala |
Transcript abundance of CAB3999162.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| apical branchlet · Control at T25 | 6 | 4 | 12.75 | 26.83 | |
| apical branchlet · Temperature treatment at T0 | 6 | 2 | 1.83 | 7.90 | |
| apical branchlet · Temperature treatment at T25 | 5 | 2 | 3.48 | 15.43 | |
| apical branchlet · Control at T0 | 4 | 1 | 2.10 | 8.40 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR19977444 | apical branchlet · Control at T25 | apical branchlet | not recorded | Control at T25 | SRP384900 | 26.83 |
| SRR19977455 | apical branchlet · Control at T25 | apical branchlet | not recorded | Control at T25 | SRP384900 | 19.58 |
| SRR19977441 | apical branchlet · Control at T25 | apical branchlet | not recorded | Control at T25 | SRP384900 | 19.56 |
| SRR19977440 | apical branchlet · Control at T25 | apical branchlet | not recorded | Control at T25 | SRP384900 | 10.55 |
| SRR19977433 | apical branchlet · Control at T25 | apical branchlet | not recorded | Control at T25 | SRP384900 | 0.00 |
| SRR19977439 | apical branchlet · Control at T25 | apical branchlet | not recorded | Control at T25 | SRP384900 | 0.00 |
| SRR19977427 | apical branchlet · Temperature treatment at T0 | apical branchlet | not recorded | Temperature treatment at T0 | SRP384900 | 7.90 |
| SRR19977438 | apical branchlet · Temperature treatment at T0 | apical branchlet | not recorded | Temperature treatment at T0 | SRP384900 | 3.06 |
| SRR19977426 | apical branchlet · Temperature treatment at T0 | apical branchlet | not recorded | Temperature treatment at T0 | SRP384900 | 0.00 |
| SRR19977428 | apical branchlet · Temperature treatment at T0 | apical branchlet | not recorded | Temperature treatment at T0 | SRP384900 | 0.00 |
| SRR19977436 | apical branchlet · Temperature treatment at T0 | apical branchlet | not recorded | Temperature treatment at T0 | SRP384900 | 0.00 |
| SRR19977437 | apical branchlet · Temperature treatment at T0 | apical branchlet | not recorded | Temperature treatment at T0 | SRP384900 | 0.00 |
| SRR19977463 | apical branchlet · Temperature treatment at T25 | apical branchlet | not recorded | Temperature treatment at T25 | SRP384900 | 15.43 |
| SRR19977435 | apical branchlet · Temperature treatment at T25 | apical branchlet | not recorded | Temperature treatment at T25 | SRP384900 | 2.00 |
| SRR19977425 | apical branchlet · Temperature treatment at T25 | apical branchlet | not recorded | Temperature treatment at T25 | SRP384900 | 0.00 |
| SRR19977432 | apical branchlet · Temperature treatment at T25 | apical branchlet | not recorded | Temperature treatment at T25 | SRP384900 | 0.00 |
| SRR19977434 | apical branchlet · Temperature treatment at T25 | apical branchlet | not recorded | Temperature treatment at T25 | SRP384900 | 0.00 |
| SRR19977443 | apical branchlet · Control at T0 | apical branchlet | not recorded | Control at T0 | SRP384900 | 8.40 |
| SRR19977442 | apical branchlet · Control at T0 | apical branchlet | not recorded | Control at T0 | SRP384900 | 0.00 |
| SRR19977445 | apical branchlet · Control at T0 | apical branchlet | not recorded | Control at T0 | SRP384900 | 0.00 |
| SRR19977446 | apical branchlet · Control at T0 | apical branchlet | not recorded | Control at T0 | SRP384900 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM,
StringTie quantification over 21 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 25 | CAB3986952.1 | 0.965472736329239 |
| Negatively correlated | 4 | CAB4037663.1 | -0.588416039980932 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
