Detailed information of CAB4000456.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB4000456.1, ribose-phosphate pyrophosphokinase 1 [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

 Sequence
No sequence record for CAB4000456.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q7ZXC9Ribose-phosphate pyrophosphokinase 2 OS=Xenopus laevis OX=8355 GN=prps2 PE=2 SV=1
Q5XGI0Ribose-phosphate pyrophosphokinase 2 OS=Xenopus tropicalis OX=8364 GN=prps2 PE=2 SV=1
Q2HJ58Ribose-phosphate pyrophosphokinase 1 OS=Bos taurus OX=9913 GN=PRPS1 PE=2 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001402 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF13793
all species →
Pribosyltran_NN-terminal domain of ribose phosphate pyrophosphokinaseDomainInterproscan
PF14572
all species →
Pribosyl_synthPhosphoribosyl synthetase-associated domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000836
all species →
DomainPhosphoribosyltransferase domainInterproscan
IPR000842
all species →
Conserved_sitePhosphoribosyl pyrophosphate synthetase, conserved siteInterproscan
IPR029057
all species →
Homologous_superfamilyPhosphoribosyltransferase-likeInterproscan
IPR029099
all species →
DomainRibose-phosphate pyrophosphokinase, N-terminal domainInterproscan
IPR005946
all species →
FamilyRibose-phosphate pyrophosphokinaseInterproscan
IPR037515
all species →
FamilyRibose-phosphate pyrophosphokinase, bacterial-typeInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10210
all species →
RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBERInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000287
all species →
Molecular Functionmagnesium ion bindingInterproscan
GO:0004749
all species →
Molecular Functionribose phosphate diphosphokinase activityInterproscan
GO:0009156
all species →
Biological Processribonucleoside monophosphate biosynthetic processInterproscan
GO:0044249
all species →
Biological Processobsolete cellular biosynthetic processInterproscan
GO:0009165
all species →
Biological Processnucleotide biosynthetic processInterproscan
GO:0002189
all species →
Cellular Componentribose phosphate diphosphokinase complexInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0006015
all species →
Biological Process5-phosphoribose 1-diphosphate biosynthetic processInterproscan
GO:0006164
all species →
Biological Processpurine nucleotide biosynthetic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00948PRPS, prsA; ribose-phosphate pyrophosphokinaseEC:2.7.6.1
Purine metabolismko00230deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB4000456.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
12TPM > 0
4Conditions
122.8Max TPM
22.7Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
apical branchlet · Control at T25 6 4 40.79 122.83
apical branchlet · Temperature treatment at T0 6 4 30.23 108.65
apical branchlet · Temperature treatment at T25 5 2 4.38 17.96
apical branchlet · Control at T0 4 2 7.32 14.89

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR19977444 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 122.83
SRR19977455 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 56.82
SRR19977441 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 46.98
SRR19977440 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 18.11
SRR19977433 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.00
SRR19977439 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.00
SRR19977428 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 108.65
SRR19977426 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 48.27
SRR19977427 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 16.00
SRR19977438 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 8.46
SRR19977436 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977437 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977435 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 17.96
SRR19977425 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 3.96
SRR19977432 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977434 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977463 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977443 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 14.89
SRR19977445 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 14.37
SRR19977442 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00
SRR19977446 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated24CAB4018683.10.982889611305388
Negatively correlated3CAB4029881.1-0.538291555179278

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.not in the sequence tableopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.not in the sequence tableopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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