Detailed information of CAB4000515.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB4000515.1, Bardet-Biedl syndrome 2 homolog [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

 Sequence
No sequence record for CAB4000515.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q98SP7BBSome complex member BBS2 OS=Danio rerio OX=7955 GN=bbs2 PE=2 SV=1
Q9CWF6BBSome complex member BBS2 OS=Mus musculus OX=10090 GN=Bbs2 PE=1 SV=1
Q99MH9BBSome complex member BBS2 OS=Rattus norvegicus OX=10116 GN=Bbs2 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004798 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF14781
all species →
BBS2_NCiliary BBSome complex subunit 2, N-terminalRepeatInterproscan
PF14783
all species →
BBS2_MidCiliary BBSome complex subunit 2, middle regionRepeatInterproscan
PF14782
all species →
BBS2_CCiliary BBSome complex subunit 2, C-terminalFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR016616
all species →
FamilyBardet-Biedl syndrome 2 proteinInterproscan
IPR029430
all species →
DomainCiliary BBSome complex subunit 2, N-terminalInterproscan
IPR029429
all species →
DomainCiliary BBSome complex subunit 2, middle regionInterproscan
IPR015943
all species →
Homologous_superfamilyWD40/YVTN repeat-like-containing domain superfamilyInterproscan
IPR029333
all species →
DomainCiliary BBSome complex subunit 2, C-terminal domainInterproscan
IPR011047
all species →
Homologous_superfamilyQuinoprotein alcohol dehydrogenase-like superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR32465
all species →
BARDET-BIEDL SYNDROME 2 PROTEINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0016020
all species →
Cellular ComponentmembraneInterproscan
GO:0031514
all species →
Cellular Componentmotile ciliumInterproscan
GO:0034464
all species →
Cellular ComponentBBSomeInterproscan
GO:0036064
all species →
Cellular Componentciliary basal bodyInterproscan
GO:0043005
all species →
Cellular Componentneuron projectionInterproscan
GO:0060271
all species →
Biological Processcilium assemblyInterproscan
GO:1905515
all species →
Biological Processnon-motile cilium assemblyInterproscan
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K16747BBS2; Bardet-Biedl syndrome 2 protein-Cilium and associated proteinsko03037deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB4000515.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
10TPM > 0
4Conditions
19.6Max TPM
5.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
apical branchlet · Control at T25 6 4 9.22 19.62
apical branchlet · Temperature treatment at T0 6 3 5.49 17.52
apical branchlet · Temperature treatment at T25 5 2 1.98 6.09
apical branchlet · Control at T0 4 1 3.50 13.99

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR19977444 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 19.62
SRR19977441 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 13.08
SRR19977440 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 12.15
SRR19977455 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 10.48
SRR19977433 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.00
SRR19977439 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.00
SRR19977428 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 17.52
SRR19977427 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 11.44
SRR19977438 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 3.97
SRR19977426 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977436 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977437 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977435 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 6.09
SRR19977425 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 3.82
SRR19977432 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977434 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977463 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977443 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 13.99
SRR19977442 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00
SRR19977445 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00
SRR19977446 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated32CAB4034095.10.976524633256124
Negatively correlated3CAB3979839.1-0.743099965970427

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.not in the sequence tableopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.not in the sequence tableopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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