Detailed information of CAB4005365.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB4005365.1, tRNA pseudouridine(38 39) synthase-like [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

 Sequence
No sequence record for CAB4005365.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q3SX07tRNA pseudouridine(38/39) synthase OS=Bos taurus OX=9913 GN=PUS3 PE=2 SV=1
Q9BZE2tRNA pseudouridine(38/39) synthase OS=Homo sapiens OX=9606 GN=PUS3 PE=1 SV=3
Q9JI38tRNA pseudouridine(38/39) synthase OS=Mus musculus OX=10090 GN=Pus3 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006374 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01416
all species →
PseudoU_synth_1tRNA pseudouridine synthaseDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR020095
all species →
Homologous_superfamilyPseudouridine synthase I, TruA, C-terminalInterproscan
IPR001406
all species →
FamilyPseudouridine synthase I, TruAInterproscan
IPR020097
all species →
DomainPseudouridine synthase I, TruA, alpha/beta domainInterproscan
IPR041707
all species →
FamilyPseudouridine synthase Pus3-likeInterproscan
IPR020094
all species →
Homologous_superfamilyPseudouridine synthase TruA/RsuA/RluB/E/F, N-terminalInterproscan
IPR020103
all species →
Homologous_superfamilyPseudouridine synthase, catalytic domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11142
all species →
PSEUDOURIDYLATE SYNTHASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003723
all species →
Molecular FunctionRNA bindingInterproscan
GO:0009982
all species →
Molecular Functionpseudouridine synthase activityInterproscan
GO:0001522
all species →
Biological Processpseudouridine synthesisInterproscan
GO:0009451
all species →
Biological ProcessRNA modificationInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0031119
all species →
Biological ProcesstRNA pseudouridine synthesisInterproscan
GO:1990481
all species →
Biological ProcessmRNA pseudouridine synthesisInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01855PUS3, DEG1; tRNA pseudouridine38/39 synthaseEC:5.4.99.45
Transfer RNA biogenesisko03016deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB4005365.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
14TPM > 0
4Conditions
33.8Max TPM
7.8Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
apical branchlet · Control at T25 6 4 8.57 25.13
apical branchlet · Temperature treatment at T0 6 4 5.08 15.74
apical branchlet · Temperature treatment at T25 5 3 8.62 25.89
apical branchlet · Control at T0 4 3 9.88 33.83

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR19977444 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 25.13
SRR19977455 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 15.55
SRR19977441 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 5.94
SRR19977440 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 4.82
SRR19977433 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.00
SRR19977439 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.00
SRR19977428 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 15.74
SRR19977427 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 7.67
SRR19977437 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 5.70
SRR19977438 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 1.36
SRR19977426 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977436 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977463 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 25.89
SRR19977432 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 16.51
SRR19977435 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.73
SRR19977425 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977434 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977445 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 33.83
SRR19977443 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 3.09
SRR19977442 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 2.58
SRR19977446 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated22CAB3989808.10.903358196466215
Negatively correlated10CAB4024323.1-0.534423160710682

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.not in the sequence tableopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.not in the sequence tableopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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