Gene detail

Detailed information of CAB4010615.1 in Paramuricea clavata

Genomic Location: pcla8_s007021:13104...15848
NR annotation: CAB4010615.1, GDH 6PGL endoplasmic bifunctional [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

PACLA_8A053915

ATGGCGACCAATTCATTATCACCGTTTATATGCAGAAAATATTTAATATTTACGTTATTTTTGGGCAATATTTTATCACAAAATCATGCTGAAAATGAGCTAAAACAGCGAATAAACATTATACTTGTGGGTGGAACCGGTGATCTGGCAAAACGGTATCTATGGAATGGATTTTTTAACCTTTATTCATCTTTGCATAACACTAATTCTGGTGACTCAGTACTTCGCTTTTATGGCGGTGCTCGCGAGGACAACGAAACGGGAAATAGAATACTCTTGGATATTTTAAACACGTCAATTAAATGCTCAAATGTTAAATGCAATAAAATGAAAGCTGAATTTATTAAACGCTGTAGTTATCACAGATTAAAAATCACAGAAGACTATGAAAGTCTTCAAAAATTATTGGAAACTAGTTTAACGAACAAGGAAACCGAGATTGGTCGTATTTTTTATCTTTCTGTTCCGCCTTTTGCTTATGAAAAAATTAGCAGGAACATTGCCGAGAAATGTCGACCAAACTCACTCCGTGCATGGGTTCGGGTTGTGCTGGAGAAGCCGTTTGGAAGCGATCTTAAGACTGCAAACGAGCTAGCTGAAAAATTGTCGAAATACTGGAACGAAGATGAGATATATCGCATTGATCATTATTTAGGAAAGGCTGGCGTGGTGCAAATTATGGAATTTAAAAAAGAAAACCTTGATTTTTTTGAAAAAATGTGGAATCGCGAACATATTGAACAAGTGAATATTGTCGTGAAAGAACGCTTAGATGCACAGGGTAGGCTGGGTTTCTATGATCAGTACGGAGTCATCCGAGATATTTTTCAGAATCATTTGACTGAGATTCTCAGCTTGGTTGCTTCGGAAATGTCTGAACACAATTCTGAAAAACCGTGTCAAGATTCTGTGAAACAGCTTGAAAATTTTGAGAAATTGATCAGAAATTCTGAGAAGCCACTTGGAAATTCTGAAAAATTGCTTGAGAATTCTGAGAAATTATTTGAATCTTCTGAAAAACTGCTTGAAAATTCTCAGAAACTGCTTGAGAACTCTGAGAAACTACTTCAAAATTCTGAAAAATTACTTGAGAAACAGCAACAAAATTCTGGGAAACCTGCTCAGAACTTTGAGAAGCATTTTACTGATTCTGAAATACTAAGTGACATTTCTGGGAAAGAGACACCTCTTAGGACTTTTGATAAACTAGCTGAAAATGAGGAGACACCTATTGGGGATTCTAAGAAACCATTTCAAAATTCTAAGAAATCTACATTGTTGAGAGCTGTGAAAACAGTTACAATACATGATGCTGTATTTGGACAATATGAAGAATACAATAAACAACTCAAGCAAGAGCTTCCAAATATTGAAGCCAATAGTAACACGCCAACATTTTCGGCAGTCGTCATGGAAATCCAAAACAAACGCTGGTCCGGTGTGCCGTTTGTCCTGCTTTCTGGCAAAAGGTTGGACAGCAGACTTGCTTACGTACAGCTAGAATTCAAACAGAATAAATTCTGTATAAAGGGTAACTTGAATAATAATCCTGAAAATTGTAAACCAAGAGAGCTTACATTTTATATTCAAGGCGAAAATGTCCATTATCCATTAACAATATTCTCAAAAAAACTACCTTATGTTAAATTTTCTAACAACTGGCAGAATCTAACCCTTGATTCTGAACTCAAATCTCAGTTCAAGGGTGAAAACATAATTATGAAACCACCGAATACTGAACACGATGCTTACAGTTCGTTAATCTGTGACGTTTTTCTTGGAAATAAAGACAAATTTGTGAATGTTGACGATTTGCTGCTATCATGGAAAATTTGGAACCCTTTGCTTGAAGCGTCTGCGTTGATTCAACCACAGTTATATACTCGAGAGAACATGAATATTTTAGATTTTGAAATTGTTGATGGAAAAATTAGATTTGTGTCAGGGTCTGCAAGTGACTGTGAAACGTCAGGACCTACAAAATATGACGATGGTCAATTGCATAGTTTCCGTGGCAACAGACTTGTTTCGGGACTTTCAATGGATGTTGTTCGACAACTTGCAAATGATATAGCTGTTGCCATTCATGCAAAAGTGCAGTCCAGTGCGGCAACATTTCATTTGGCTTTATCCGGTGGTTCAACTTCAAAGCATCTTTTCCAAGTGTTGGCTTCAATTAAATATATTCCTTGGAAAAACGTGCACATATGGTTGGTCGATGAACGATGTGTAAGTTTGACGCATGAGGATTCAAATTTTAAAAATATGTATCAACACTTGTTAAAAGATATCTCGATTCCATATTTCAACATCCATCCTATGCCTGTCGATATCGCTGGGCAATTTTGTAAGCCTAACGACTTAGGGGACAAGCATTATGAGAGGCAATTAAGATACCTCGTTAATGGCTCGTTAGACTTTGTTGTATTAGGCGTTGGTAACGACGGTCATACTGCATCTTTGTTTCCTGGAAGTGACTTGTTAACGAGTACTAATTGGGTTGAGATAACGAGCTCGTTAGGAAATTATAATAGGATGACAATGACTCTGCGGATATTGAACCAGGCCAGAAACATCGCAGTGCTTATACTGGGGGAGAAGAAACATGAAATTGTTCAGAAGTTAGCGCAAACTGGTAACGATATTCATGATTTTCCAATAACTGCAGTAAAGCCAGAGCATGGTTCGTTAGTGTGGTACATAGATGATAATGCATTGCATTATGCAACGTTGGTCACGCTGTAA

Transcript

rna-PACLA_8A053915

ATGGCGACCAATTCATTATCACCGTTTATatgcagaaaatatttaatatttacgtTATTTTTGGgcaatattttatcacaaaatCATGCTGAAAATGAGCTAAAACAGCGAATAAACATTATACTTGTGGGTGGAACCGGTGATCTGGCAAAACGGTATCTATGGAATGGATTTTTTAACCTTTATTCATCTTTGCATAACACTAATTCTGGTGACTCAGTACTTCGCTTTTATGGCGGTGCTCGCGAGGACAACGAAACGGGAAATAGAATACTCTTGGATATTTTAAACACGTCAATTAAATGCTCAAATGTTAAATGCAATAAAATGAAAGCTGAATTTATTAAACGCTGTAGTTATCACAGATTAAAAATCACAGAAGACTATGAAAGTCTTCAAAAATTATTGGAAACTAGTTTAACGAACAAGGAAACCGAGATTGGTCGTATTTTTTATCTTTCTGTTCCGCCTTTTGCTTATGAAAAAATTAGCAGGAACATTGCCGAGAAATGTCGACCAAACTCACTCCGTGCATGGGTTCGGGTTGTGCTGGAGAAGCCGTTTGGAAGCGATCTTAAGACTGCAAACGAGCTAGCTGAAAAATTGTCGAAATACTGGAACGAAGATGAGATATATCGCATTGATCATTATTTAGGAAAGGCTGGCGTGGTGCAAATTATGgaatttaaaaaagaaaaccttgatttttttgaaaaaatgtggAATCGCGAACATATTGAACAAGTGAATATTGTCGTGAAAGAACGCTTAGATGCACAGGGTAGGCTGGGTTTCTATGATCAGTACGGAGTCATCCGAGATATTTTTCAGAATCATTTGACTGAGATTCTCAGCTTGGTTGCTTCGGAAATGTCTGAACACAATTCTGAAAAACCGTGTCAAGATTCTGTGAAACAGcttgaaaattttgagaaatTGATCAGAAATTCTGAGAAGCCACTTGGAAATTCTGAAAAATTGCTTGAGAATTCTGAGAAATTATTTGAATCTTCTGAAAAACTGCTTGAAAATTCTCAGAAACTGCTTGAGAACTCTGAGAAACTACTTCAAAATTCTGAAAAATTACTTGAGAAACAGCAACAAAATTCTGGGAAACCTGCTCAGAACTTTGAGAAGCATTTTACTGATTCTGAAATACTAAGTGACATTTCTGGGAAAGAGACACCTCTTAGGACTTTTGATAAACTAGCTGAAAATGAGGAGACACCTATTGGGGATTCTAAGAAACCATTTCAAAATTCTAAGAAATCTACATTGTTGAGAGCTGTGAAAACAGTTACAATACATGATGCTGTATTTGGACAATATGAAGAATACAATAAACAACTCAAGCAAGAGCTTCCAAATATTGAAGCCAATAGTAACACGCCAACATTTTCGGCAGTCGTCATGGAAATCCAAAACAAACGCTGGTCCGGTGTGCCGTTTGTCCTGCTTTCTGGCAAAAGGTTGGACAGCAGACTTGCTTACGTACAGCTAGAATTCAAACAGAATAAATTCTGTATAAAGGGTAACTTGAATAATAATCCTGAAAATTGTAAACCAAGAGAGCTTACATTTTATATTCAAGGCGAAAATGTCCATTATCCATTAACAATATTCTCAAAAAAACTACCTTATGTTAAATTTTCTAACAACTGGCAGAATCTAACCCTTGATTCTGAACTCAAATCTCAGTTCAAGGGTGAAAACATAATTATGAAACCACCGAATACTGAACACGATGCTTACAGTTCGTTAATCTGTGACGTTTTTCTTGGAAATAAAGACAAATTTGTGAATGTTGACGATTTGCTGCTATCATGGAAAATTTGGAACCCTTTGCTTGAAGCGTCTGCGTTGATTCAACCACAGTTATATACTCGAGAGAACATGAATATTTTAGATTTTGAAATTGTTGATGGAAAAATTAGATTTGTGTCAGGGTCTGCAAGTGACTGTGAAACGTCAGGACCTACAAAATATGACGATGGTCAATTGCATAGTTTCCGTGGCAACAGACTTGTTTCGGGACTTTCAATGGATGTTGTTCGACAACTTGCAAATGATATAGCTGTTGCCATTCATGCAAAAGTGCAGTCCAGTGCGGCAACATTTCATTTGGCTTTATCCGGTGGTTCAACTTCAAAGCATCTTTTCCAAGTGTTGGCTTCAATTAAATATATTCCTTGGAAAAACGTGCACATATGGTTGGTCGATGAACGATGTGTAAGTTTGACGCATgaggattcaaattttaaaaatatgtatcAACACTTGTTAAAAGATATCTCGATTCCATATTTCAACATCCATCCTATGCCTGTCGATATCGCTGGGCAATTTTGTAAGCCTAACGACTTAGGGGACAAGCATTATGAGAGGCAATTAAGATACCTCGTTAATGGCTCGTTAGACTTTGTTGTATTAGGCGTTGGTAACGACGGTCATACTGCATCTTTGTTTCCTGGAAGTGACTTGTTAACGAGTACTAATTGGGTTGAGATAACGAGCTCGTTAGGAAATTATAATAGGATGACAATGACTCTGCGGATATTGAACCAGGCCAGAAACATCGCAGTGCTTATACTGGGGGAGAAGAAACATGAAATTGTTCAGAAGTTAGCGCAAACTGGTAACGATATTCATGATTTTCCAATAACTGCAGTAAAGCCAGAGCATGGTTCGTTAGTGTGGTACATAGATGATAATGCATTGCATTATGCAACGTTGGTCACGCTGTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O95479	GDH/6PGL endoplasmic bifunctional protein OS=Homo sapiens OX=9606 GN=H6PD PE=1 SV=2
Q8CFX1	GDH/6PGL endoplasmic bifunctional protein OS=Mus musculus OX=10090 GN=H6pd PE=1 SV=2
P56201	GDH/6PGL endoplasmic bifunctional protein OS=Oryctolagus cuniculus OX=9986 GN=H6PD PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0009484 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02781 all species →	G6PD_C	Glucose-6-phosphate dehydrogenase, C-terminal domain	Domain	Interproscan
PF01182 all species →	Glucosamine_iso	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	Domain	Interproscan
PF00479 all species →	G6PD_N	Glucose-6-phosphate dehydrogenase, NAD binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR037171 all species →	Homologous_superfamily	NagB/RpiA transferase-like	Interproscan
IPR001282 all species →	Family	Glucose-6-phosphate dehydrogenase	Interproscan
IPR005900 all species →	Domain	6-phosphogluconolactonase, DevB-type	Interproscan
IPR022675 all species →	Domain	Glucose-6-phosphate dehydrogenase, C-terminal	Interproscan
IPR006148 all species →	Domain	Glucosamine/galactosamine-6-phosphate isomerase	Interproscan
IPR022674 all species →	Domain	Glucose-6-phosphate dehydrogenase, NAD-binding	Interproscan
IPR036291 all species →	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23429 all species →	GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004345 all species →	Molecular Function	glucose-6-phosphate dehydrogenase activity	Interproscan
GO:0005783 all species →	Cellular Component	endoplasmic reticulum	Interproscan
GO:0006006 all species →	Biological Process	glucose metabolic process	Interproscan
GO:0009051 all species →	Biological Process	pentose-phosphate shunt, oxidative branch	Interproscan
GO:0016614 all species →	Molecular Function	oxidoreductase activity, acting on CH-OH group of donors	Interproscan
GO:0050661 all species →	Molecular Function	NADP binding	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0006098 all species →	Biological Process	pentose-phosphate shunt	Interproscan
GO:0017057 all species →	Molecular Function	6-phosphogluconolactonase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K13937	H6PD; hexose-6-phosphate dehydrogenase	EC:1.1.1.47 EC:3.1.1.31	Pentose phosphate pathway	ko00030	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB4010615.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples

10TPM > 0

4Conditions

16.7Max TPM

1.8Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
apical branchlet · Control at T25	6	4	1.83	3.59
apical branchlet · Temperature treatment at T0	6	3	1.34	5.41
apical branchlet · Temperature treatment at T25	5	1	0.23	1.17
apical branchlet · Control at T0	4	2	4.49	16.71

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR19977444	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	3.59
SRR19977441	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	2.74
SRR19977440	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	2.46
SRR19977455	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	2.22
SRR19977433	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.00
SRR19977439	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	0.00
SRR19977428	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	5.41
SRR19977427	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	1.63
SRR19977438	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	1.02
SRR19977426	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977436	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977437	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	0.00
SRR19977435	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	1.17
SRR19977425	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977432	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977434	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977463	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	0.00
SRR19977445	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	16.71
SRR19977443	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	1.26
SRR19977442	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00
SRR19977446	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.