Detailed information of CAB4010674.1 in Paramuricea clavata

Genomic Location: pcla8_s007043:6814...8649
NR annotation: CAB4010674.1, collagen alpha-1(XIV) chain-like [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
A2AX52Collagen alpha-4(VI) chain OS=Mus musculus OX=10090 GN=Col6a4 PE=1 SV=2
P13944Collagen alpha-1(XII) chain OS=Gallus gallus OX=9031 GN=COL12A1 PE=1 SV=3
P15989Collagen alpha-3(VI) chain OS=Gallus gallus OX=9031 GN=COL6A3 PE=2 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0007506 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00092
all species →
VWAvon Willebrand factor type A domainDomainInterproscan
PF16754
all species →
PesticinBacterial toxin homologue of phage lysozyme, C-termDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR002035
all species →
Domainvon Willebrand factor, type AInterproscan
IPR031922
all species →
DomainPesticin, C-terminalInterproscan
IPR050525
all species →
FamilyExtracellular Matrix Assembly and OrganizationInterproscan
IPR023347
all species →
Homologous_superfamilyLysozyme domain superfamilyInterproscan
IPR023346
all species →
Homologous_superfamilyLysozyme-like domain superfamilyInterproscan
IPR036465
all species →
Homologous_superfamilyvon Willebrand factor A-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR24020
all species →
COLLAGEN ALPHAInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003796
all species →
Molecular Functionlysozyme activityInterproscan
GO:0062023
all species →
Cellular Componentcollagen-containing extracellular matrixInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for CAB4010674.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB4010674.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
15TPM > 0
4Conditions
35.9Max TPM
4.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
apical branchlet · Control at T25 6 6 4.98 14.75
apical branchlet · Temperature treatment at T0 6 4 7.55 35.86
apical branchlet · Temperature treatment at T25 5 3 1.59 4.14
apical branchlet · Control at T0 4 2 2.53 7.93

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR19977439 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 14.75
SRR19977433 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 8.83
SRR19977440 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 4.16
SRR19977441 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 1.15
SRR19977444 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.55
SRR19977455 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.43
SRR19977436 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 35.86
SRR19977428 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 4.79
SRR19977438 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 3.55
SRR19977427 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 1.12
SRR19977426 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977437 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977432 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 4.14
SRR19977425 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 2.29
SRR19977435 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 1.53
SRR19977434 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977463 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977443 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 7.93
SRR19977442 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 2.17
SRR19977445 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00
SRR19977446 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated8CAB4015475.10.947350059014537
Negatively correlated8CAB4016721.1-0.489795859211878

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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