Detailed information of CAB4015893.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB4015893.1, asparagine--tRNA ligase, cytoplasmic isoform X2 [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

 Sequence
No sequence record for CAB4015893.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q2KJG3Asparagine--tRNA ligase, cytoplasmic OS=Bos taurus OX=9913 GN=NARS PE=2 SV=3
O43776Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1
Q8BP47Asparagine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Nars1 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002557 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF20917
all species →
AsnRS_NAsparaginal-tRNA synthetase, N-terminal domainDomainInterproscan
PF01336
all species →
tRNA_anti-codonOB-fold nucleic acid binding domainDomainInterproscan
PF00152
all species →
tRNA-synt_2tRNA synthetases class II (D, K and N) DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR006195
all species →
DomainAminoacyl-tRNA synthetase, class IIInterproscan
IPR048952
all species →
DomainAsparagine--tRNA ligase, N-terminal domainInterproscan
IPR004365
all species →
DomainOB-fold nucleic acid binding domain, AA-tRNA synthetase-typeInterproscan
IPR012340
all species →
Homologous_superfamilyNucleic acid-binding, OB-foldInterproscan
IPR045864
all species →
Homologous_superfamilyClass II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)Interproscan
IPR002312
all species →
FamilyAspartyl/Asparaginyl-tRNA synthetase, class IIbInterproscan
IPR004522
all species →
FamilyAsparagine-tRNA ligaseInterproscan
IPR004364
all species →
DomainAminoacyl-tRNA synthetase, class II (D/K/N)Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR22594
all species →
ASPARTYL/LYSYL-TRNA SYNTHETASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004816
all species →
Molecular Functionasparagine-tRNA ligase activityInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0006421
all species →
Biological Processasparaginyl-tRNA aminoacylationInterproscan
GO:0003676
all species →
Molecular Functionnucleic acid bindingInterproscan
GO:0000166
all species →
Molecular Functionnucleotide bindingInterproscan
GO:0004812
all species →
Molecular Functionaminoacyl-tRNA ligase activityInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0006418
all species →
Biological ProcesstRNA aminoacylation for protein translationInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01893NARS, asnS; asparaginyl-tRNA synthetaseEC:6.1.1.22
Transfer RNA biogenesisko03016deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB4015893.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
21TPM > 0
4Conditions
1,538.8Max TPM
594.8Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
apical branchlet · Control at T25 6 6 585.33 943.92
apical branchlet · Temperature treatment at T0 6 6 569.02 1,533.33
apical branchlet · Temperature treatment at T25 5 5 275.54 742.01
apical branchlet · Control at T0 4 4 1,046.81 1,538.84

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR19977439 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 943.92
SRR19977455 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 667.79
SRR19977441 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 536.34
SRR19977433 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 509.51
SRR19977444 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 436.37
SRR19977440 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 418.03
SRR19977427 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 1,533.33
SRR19977438 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 766.46
SRR19977437 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 449.50
SRR19977428 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 432.67
SRR19977436 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 165.39
SRR19977426 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 66.77
SRR19977435 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 742.01
SRR19977432 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 247.52
SRR19977463 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 173.62
SRR19977434 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 124.42
SRR19977425 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 90.16
SRR19977443 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 1,538.84
SRR19977445 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 1,344.96
SRR19977442 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 718.09
SRR19977446 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 585.33

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated19CAB4008800.10.880878456162291
Negatively correlated19CAB3987558.1-0.639443472184526

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.not in the sequence tableopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.not in the sequence tableopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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