Gene detail

Detailed information of CAB4016231.1 in Paramuricea clavata

Genomic Location: not available for this species
NR annotation: CAB4016231.1, ubiquitin-like modifier-activating enzyme 1 [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families

Sequence

No sequence record for CAB4016231.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q29504	Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus cuniculus OX=9986 GN=UBA1 PE=1 SV=1
P22314	Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3
A3KMV5	Ubiquitin-like modifier-activating enzyme 1 OS=Bos taurus OX=9913 GN=UBA1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001434 (this species only)
Ubiquitin family	E1\|ThiF\|ThiF · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16191 all species →	E1_4HB	Ubiquitin-activating enzyme E1 four-helix bundle	Domain	Interproscan
PF10585 all species →	UBA_E1_SCCH	Ubiquitin-activating enzyme, SCCH domain	Domain	Interproscan
PF09358 all species →	E1_UFD	Ubiquitin fold domain	Domain	Interproscan
PF00899 all species →	ThiF	ThiF family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR033127 all species →	Active_site	Ubiquitin-activating enzyme E1, Cys active site	Interproscan
IPR032420 all species →	Domain	Ubiquitin-activating enzyme E1, four-helix bundle	Interproscan
IPR035985 all species →	Homologous_superfamily	Ubiquitin-activating enzyme	Interproscan
IPR018075 all species →	Family	Ubiquitin-activating enzyme E1	Interproscan
IPR045886 all species →	Family	ThiF/MoeB/HesA family	Interproscan
IPR019572 all species →	Domain	Ubiquitin-activating enzyme, SCCH domain	Interproscan
IPR018965 all species →	Domain	Ubiquitin-activating enzyme E1, C-terminal	Interproscan
IPR038252 all species →	Homologous_superfamily	Ubiquitin-activating enzyme E1, C-terminal domain superfamily	Interproscan
IPR042063 all species →	Homologous_superfamily	Ubiquitin-activating enzyme E1, SCCH domain	Interproscan
IPR018074 all species →	Conserved_site	Ubiquitin-activating enzyme E1, conserved site	Interproscan
IPR000594 all species →	Domain	THIF-type NAD/FAD binding fold	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10953 all species →	UBIQUITIN-ACTIVATING ENZYME E1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0008641 all species →	Molecular Function	ubiquitin-like modifier activating enzyme activity	Interproscan
GO:0004839 all species →	Molecular Function	ubiquitin activating enzyme activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006511 all species →	Biological Process	ubiquitin-dependent protein catabolic process	Interproscan
GO:0006974 all species →	Biological Process	DNA damage response	Interproscan
GO:0016567 all species →	Biological Process	protein ubiquitination	Interproscan
GO:0032446 all species →	Biological Process	protein modification by small protein conjugation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K03178	UBE1, UBA1; ubiquitin-activating enzyme E1	EC:6.2.1.45	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB4016231.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples

20TPM > 0

4Conditions

181.7Max TPM

54.5Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
apical branchlet · Control at T25	6	6	71.48	132.88
apical branchlet · Temperature treatment at T0	6	6	43.92	124.55
apical branchlet · Temperature treatment at T25	5	5	70.92	181.70
apical branchlet · Control at T0	4	3	24.38	56.82

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR19977444	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	132.88
SRR19977441	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	91.62
SRR19977455	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	80.79
SRR19977440	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	53.34
SRR19977433	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	40.41
SRR19977439	apical branchlet · Control at T25	apical branchlet	not recorded	Control at T25	SRP384900	29.83
SRR19977428	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	124.55
SRR19977427	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	44.41
SRR19977436	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	43.97
SRR19977426	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	23.03
SRR19977438	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	21.08
SRR19977437	apical branchlet · Temperature treatment at T0	apical branchlet	not recorded	Temperature treatment at T0	SRP384900	6.49
SRR19977434	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	181.70
SRR19977463	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	68.06
SRR19977435	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	61.59
SRR19977432	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	25.93
SRR19977425	apical branchlet · Temperature treatment at T25	apical branchlet	not recorded	Temperature treatment at T25	SRP384900	17.32
SRR19977443	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	56.82
SRR19977445	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	34.20
SRR19977442	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	6.50
SRR19977446	apical branchlet · Control at T0	apical branchlet	not recorded	Control at T0	SRP384900	0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.