Detailed information of CAB4021527.1 in Paramuricea clavata

Genomic Location: pcla8_s011971:7266...7838
NR annotation: CAB4021527.1, F-box only 36-like [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8NEA4F-box only protein 36 OS=Homo sapiens OX=9606 GN=FBXO36 PE=1 SV=2
Q5R796F-box only protein 36 OS=Pongo abelii OX=9601 GN=FBXO36 PE=2 SV=1
Q9CQ24F-box only protein 36 OS=Mus musculus OX=10090 GN=Fbxo36 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002980 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF12937
all species →
F-box-likeF-box-likeDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR001810
all species →
DomainF-box domainInterproscan
IPR052301
all species →
FamilySCF Complex F-box/Wd Repeat-Containing ProteinInterproscan
IPR036047
all species →
Homologous_superfamilyF-box-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR14381
all species →
DACTYLINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan
GO:0019005
all species →
Cellular ComponentSCF ubiquitin ligase complexInterproscan
GO:0031146
all species →
Biological ProcessSCF-dependent proteasomal ubiquitin-dependent protein catabolic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10312FBXO36; F-box protein 36-Ubiquitin systemko04121deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of CAB4021527.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
13TPM > 0
4Conditions
34.9Max TPM
5.7Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
apical branchlet · Control at T25 6 5 9.62 34.87
apical branchlet · Temperature treatment at T0 6 4 5.14 20.73
apical branchlet · Temperature treatment at T25 5 2 3.56 12.18
apical branchlet · Control at T0 4 2 3.29 10.40

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR19977444 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 34.87
SRR19977439 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 8.54
SRR19977441 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 7.30
SRR19977440 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 4.20
SRR19977455 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 2.83
SRR19977433 apical branchlet · Control at T25 apical branchlet not recorded Control at T25 SRP384900 0.00
SRR19977426 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 20.73
SRR19977427 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 6.40
SRR19977438 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 2.76
SRR19977437 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.97
SRR19977428 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977436 apical branchlet · Temperature treatment at T0 apical branchlet not recorded Temperature treatment at T0 SRP384900 0.00
SRR19977432 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 12.18
SRR19977435 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 5.63
SRR19977425 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977434 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977463 apical branchlet · Temperature treatment at T25 apical branchlet not recorded Temperature treatment at T25 SRP384900 0.00
SRR19977445 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 10.40
SRR19977443 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 2.75
SRR19977442 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00
SRR19977446 apical branchlet · Control at T0 apical branchlet not recorded Control at T0 SRP384900 0.00

Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Paramuricea clavata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated9CAB4005087.10.899790404709013
Negatively correlated4CAB3976923.1-0.503557343314811

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paramuricea clavata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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