Genomic Location: pcla8_s013518:11588...12085
NR annotation: CAB4024179.1, bis(5 -adenosyl)-triphosphatase isoform X4 [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families
| CDS |
| PACLA_8A057474 |
| Transcript |
| rna-PACLA_8A057474 |
| Protein |
| CAB4024179.1 |
| UniProt accession | Description |
|---|---|
| P49789 | Bis(5'-adenosyl)-triphosphatase OS=Homo sapiens OX=9606 GN=FHIT PE=1 SV=3 |
| Q1KZG4 | Bis(5'-adenosyl)-triphosphatase OS=Bos taurus OX=9913 GN=FHIT PE=2 SV=1 |
| Q9JIX3 | Bis(5'-adenosyl)-triphosphatase OS=Rattus norvegicus OX=10116 GN=Fhit PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0009064 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01230 all species → | HIT | HIT domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036265 all species → | Homologous_superfamily | HIT-like superfamily | Interproscan |
| IPR019808 all species → | Conserved_site | Histidine triad, conserved site | Interproscan |
| IPR052677 all species → | Family | Dinucleoside polyphosphate hydrolase | Interproscan |
| IPR011146 all species → | Domain | HIT-like domain | Interproscan |
| IPR039383 all species → | Family | FHIT family | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46981 all species → | BIS(5'-ADENOSYL)-TRIPHOSPHATASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0006163 all species → | Biological Process | purine nucleotide metabolic process | Interproscan |
| GO:0015964 all species → | Biological Process | diadenosine triphosphate catabolic process | Interproscan |
| GO:0031625 all species → | Molecular Function | ubiquitin protein ligase binding | Interproscan |
| GO:0032435 all species → | Biological Process | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0047710 all species → | Molecular Function | bis(5'-adenosyl)-triphosphatase activity | Interproscan |
| GO:0072332 all species → | Biological Process | intrinsic apoptotic signaling pathway by p53 class mediator | Interproscan |
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01522 | FHIT; bis(5'-adenosyl)-triphosphatase | EC:3.6.1.29 | Non-small cell lung cancer | ko05223 | deepkoala |
Transcript abundance of CAB4024179.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| apical branchlet · Control at T25 | 6 | 5 | 142.77 | 326.31 | |
| apical branchlet · Temperature treatment at T0 | 6 | 5 | 103.42 | 287.91 | |
| apical branchlet · Temperature treatment at T25 | 5 | 4 | 83.22 | 126.82 | |
| apical branchlet · Control at T0 | 4 | 3 | 292.30 | 791.05 |
Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM,
StringTie quantification over 21 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.