Genomic Location: :...
NR annotation: CAB4037107.1, serine threonine- kinase endoribonuclease IRE1 [Paramuricea clavata]
| CDS | ||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| P32361 | Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=IRE1 PE=1 SV=2 |
| G0RBE3 | Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Hypocrea jecorina (strain QM6a) OX=431241 GN=IRE1 PE=2 SV=1 |
| Q55GJ2 | Probable serine/threonine-protein kinase ireA OS=Dictyostelium discoideum OX=44689 GN=ireA PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF05049 | IIGP | Interferon-inducible GTPase (IIGP) | Family | Interproscan |
| PF06479 | Ribonuc_2-5A | Ribonuclease 2-5A | Family | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR038357 | Homologous_superfamily | KEN domain superfamily | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR030385 | Domain | IRG-type guanine nucleotide-binding (G) domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR007743 | Family | Immunity-related GTPases-like | Interproscan |
| IPR045133 | Family | Serine/threonine-protein kinase/endoribonuclease IRE1/2-like | Interproscan |
| IPR010513 | Domain | KEN domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13954 | IRE1-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0004521 | Molecular Function | RNA endonuclease activity | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0030968 | Biological Process | endoplasmic reticulum unfolded protein response | Interproscan |
| GO:0036498 | Biological Process | IRE1-mediated unfolded protein response | Interproscan |
| GO:0051082 | Molecular Function | unfolded protein binding | Interproscan |
| GO:0070059 | Biological Process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | Interproscan |
| GO:1990604 | Cellular Component | IRE1-TRAF2-ASK1 complex | Interproscan |
| GO:0004540 | Molecular Function | RNA nuclease activity | Interproscan |
| GO:0006397 | Biological Process | mRNA processing | Interproscan |