Genomic Location: not available for this species
NR annotation: CAB4037990.1, probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Paramuricea clavata]
Species Paramuricea clavata · all data for this species · gene families
CAB4037990.1 in PCLAV (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| A7MB35 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Bos taurus OX=9913 GN=PDHA1 PE=2 SV=1 |
| P35486 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Mus musculus OX=10090 GN=Pdha1 PE=1 SV=1 |
| P26284 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Rattus norvegicus OX=10116 GN=Pdha1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004452 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00676 all species → | E1_dh | Dehydrogenase E1 component | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR050642 all species → | Family | Pyruvate Dehydrogenase E1 Alpha Subunit | Interproscan |
| IPR001017 all species → | Domain | Dehydrogenase, E1 component | Interproscan |
| IPR029061 all species → | Homologous_superfamily | Thiamin diphosphate-binding fold | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11516 all species → | PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004739 all species → | Molecular Function | pyruvate dehydrogenase (acetyl-transferring) activity | Interproscan |
| GO:0006086 all species → | Biological Process | acetyl-CoA biosynthetic process from pyruvate | Interproscan |
| GO:0016624 all species → | Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00161 | PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha | EC:1.2.4.1 | Diabetic cardiomyopathy | ko05415 | deepkoala |
Transcript abundance of CAB4037990.1 across 21 RNA-seq samples of Paramuricea clavata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| apical branchlet · Control at T25 | 6 | 6 | 85.08 | 157.17 | |
| apical branchlet · Temperature treatment at T0 | 6 | 4 | 63.64 | 191.13 | |
| apical branchlet · Temperature treatment at T25 | 5 | 3 | 36.30 | 94.62 | |
| apical branchlet · Control at T0 | 4 | 3 | 41.84 | 66.02 |
Source: CnidoSite RNA-seq expression matrices (PCLAV_TPM,
StringTie quantification over 21 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.