Genomic Location: :...
NR annotation: MXX74125.1, homoaconitate hydratase family protein [Holophagales bacterium]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q8TVF2 | 3-isopropylmalate dehydratase large subunit 1 OS=Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) OX=190192 GN=leuC1 PE=3 SV=1 |
| Q9ZNE0 | Homoaconitase large subunit OS=Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) OX=262724 GN=hacA PE=1 SV=1 |
| Q8PZT3 | Probable methanogen homoaconitase large subunit OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) OX=192952 GN=hacA PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00330 | Aconitase | Aconitase family (aconitate hydratase) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR018136 | Binding_site | Aconitase family, 4Fe-4S cluster binding site | Interproscan |
| IPR015931 | Homologous_superfamily | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 | Interproscan |
| IPR011826 | Family | Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic | Interproscan |
| IPR001030 | Domain | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain | Interproscan |
| IPR006251 | Family | Homoaconitase/3-isopropylmalate dehydratase, large subunit | Interproscan |
| IPR050067 | Family | Isopropylmalate dehydratase and related enzymes | Interproscan |
| IPR036008 | Homologous_superfamily | Aconitase, iron-sulfur domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43822 | HOMOACONITASE, MITOCHONDRIAL-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003861 | Molecular Function | 3-isopropylmalate dehydratase activity | Interproscan |
| GO:0009098 | Biological Process | L-leucine biosynthetic process | Interproscan |
| GO:0051539 | Molecular Function | 4 iron, 4 sulfur cluster binding | Interproscan |
| GO:0008652 | Biological Process | amino acid biosynthetic process | Interproscan |
| GO:0016836 | Molecular Function | hydro-lyase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01703 | leuC, IPMI-L; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | EC:4.2.1.33 EC:4.2.1.35 | Glucosinolate biosynthesis | ko00966 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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