Genomic Location: :...
NR annotation: 6ALB_A, CREBBP bromodomain in complex with Cpd 30 (1-(3-(3-(1-methyl-1H-pyrazol-4-yl)isoquinolin-8-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one) [Homo sapiens]
| CDS | ||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| P45481 | Histone lysine acetyltransferase CREBBP OS=Mus musculus OX=10090 GN=Crebbp PE=1 SV=3 |
| Q92793 | CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 |
| Q6JHU9 | Histone lysine acetyltransferase CREBBP OS=Rattus norvegicus OX=10116 GN=Crebbp PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06001 | RING_CBP-p300 | CREB-binding protein/p300, atypical RING domain | Domain | Interproscan |
| PF00439 | Bromodomain | Bromodomain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036427 | Homologous_superfamily | Bromodomain-like superfamily | Interproscan |
| IPR010303 | Domain | CREB-binding protein/p300, atypical RING domain | Interproscan |
| IPR001487 | Domain | Bromodomain | Interproscan |
| IPR013178 | Family | Histone acetyltransferase Rtt109/CBP | Interproscan |
| IPR038547 | Homologous_superfamily | CBP/p300, atypical RING domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13808 | CBP/P300-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0000123 | Cellular Component | histone acetyltransferase complex | Interproscan |
| GO:0003713 | Molecular Function | transcription coactivator activity | Interproscan |
| GO:0004402 | Molecular Function | histone acetyltransferase activity | Interproscan |
| GO:0005667 | Cellular Component | transcription regulator complex | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0016573 | Biological Process | obsolete histone acetylation | Interproscan |
| GO:0031490 | Molecular Function | chromatin DNA binding | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |