Genomic Location: :...
NR annotation: XP_012558688.1, serine/threonine-protein kinase/endoribonuclease IRE1 [Hydra vulgaris]
| CDS | ||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q9EQY0 | Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Mus musculus OX=10090 GN=Ern1 PE=1 SV=1 |
| O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Homo sapiens OX=9606 GN=ERN1 PE=1 SV=2 |
| Q09499 | Serine/threonine-protein kinase/endoribonuclease ire-1 OS=Caenorhabditis elegans OX=6239 GN=ire-1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| -- | -- | -- | -- | -- |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR018391 | Repeat | Pyrrolo-quinoline quinone beta-propeller repeat | Interproscan |
| IPR011047 | Homologous_superfamily | Quinoprotein alcohol dehydrogenase-like superfamily | Interproscan |
| IPR045133 | Family | Serine/threonine-protein kinase/endoribonuclease IRE1/2-like | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13954 | IRE1-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004521 | Molecular Function | RNA endonuclease activity | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0030968 | Biological Process | endoplasmic reticulum unfolded protein response | Interproscan |
| GO:0036498 | Biological Process | IRE1-mediated unfolded protein response | Interproscan |
| GO:0051082 | Molecular Function | unfolded protein binding | Interproscan |
| GO:0070059 | Biological Process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | Interproscan |
| GO:1990604 | Cellular Component | IRE1-TRAF2-ASK1 complex | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |