Genomic Location: WHPX01000883.1:184272...202590
NR annotation: XP_031549497.1, uncharacterized protein LOC116287026 [Actinia tenebrosa]
| CDS | |||||
| EGACTEQ4350009688-PA | |||||
| Transcript |
| EGACTEQ4350009688-PA |
| Protein |
| EGACTEQ4350009688-PA |
| Uniprot term | Description |
|---|---|
| Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3 |
| Q8INR6 | Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Drosophila melanogaster OX=7227 GN=gpp PE=1 SV=2 |
| Q6AW06 | Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Caenorhabditis elegans OX=6239 GN=dot-1.1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08123 | DOT1 | Histone methylation protein DOT1 | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR025789 | Domain | Histone-lysine N-methyltransferase DOT1 domain | Interproscan |
| IPR029063 | Homologous_superfamily | S-adenosyl-L-methionine-dependent methyltransferase superfamily | Interproscan |
| IPR030445 | Family | Histone H3-K79 methyltransferase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21451 | HISTONE H3 METHYLTRANSFERASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0031151 | Molecular Function | histone H3K79 methyltransferase activity | Interproscan |
| GO:0000077 | Biological Process | DNA damage checkpoint signaling | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0051726 | Biological Process | regulation of cell cycle | Interproscan |
| GO:2000677 | Biological Process | regulation of transcription regulatory region DNA binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11427 | DOT1L, DOT1; [histone H3]-lysine79 N-trimethyltransferase | EC:2.1.1.360 | Chromosome and associated proteins | ko03036 | deepkoala |