Genomic Location: WHPX01000784.1:267673...280206
NR annotation: XP_031558032.1, neurogenic locus notch homolog protein 2-like isoform X2 [Actinia tenebrosa]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q04721 | Neurogenic locus notch homolog protein 2 OS=Homo sapiens OX=9606 GN=NOTCH2 PE=1 SV=3 |
| O35516 | Neurogenic locus notch homolog protein 2 OS=Mus musculus OX=10090 GN=Notch2 PE=1 SV=2 |
| Q9QW30 | Neurogenic locus notch homolog protein 2 OS=Rattus norvegicus OX=10116 GN=Notch2 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12661 | hEGF | Human growth factor-like EGF | Domain | Interproscan |
| PF07684 | NODP | NOTCH protein | Family | Interproscan |
| PF00066 | Notch | LNR domain | Domain | Interproscan |
| PF07645 | EGF_CA | Calcium-binding EGF domain | Domain | Interproscan |
| PF00008 | EGF | EGF-like domain | Domain | Interproscan |
| PF13857 | Ank_5 | Ankyrin repeats (many copies) | Repeat | Interproscan |
| PF06816 | NOD | NOTCH protein | Family | Interproscan |
| PF00023 | Ank | Ankyrin repeat | Repeat | Interproscan |
| PF12796 | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR051355 | Family | Notch and Slit guidance protein | Interproscan |
| IPR000742 | Domain | EGF-like domain | Interproscan |
| IPR035993 | Homologous_superfamily | Notch-like domain superfamily | Interproscan |
| IPR024600 | Domain | Notch, C-terminal | Interproscan |
| IPR000152 | PTM | EGF-type aspartate/asparagine hydroxylation site | Interproscan |
| IPR009030 | Homologous_superfamily | Growth factor receptor cysteine-rich domain superfamily | Interproscan |
| IPR018097 | Conserved_site | EGF-like calcium-binding, conserved site | Interproscan |
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR013032 | Conserved_site | EGF-like, conserved site | Interproscan |
| IPR001881 | Domain | EGF-like calcium-binding domain | Interproscan |
| IPR000800 | Domain | Notch domain | Interproscan |
| IPR011656 | Domain | Notch, NODP domain | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR049883 | Domain | NOTCH1 EGF-like calcium-binding domain | Interproscan |
| IPR008297 | Family | Notch | Interproscan |
| IPR010660 | Domain | Notch, NOD domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45836 | SLIT HOMOLOG | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007219 | Biological Process | Notch signaling pathway | Interproscan |
| GO:0007411 | Biological Process | axon guidance | Interproscan |
| GO:0009986 | Cellular Component | cell surface | Interproscan |
| GO:0043235 | Cellular Component | receptor complex | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0007275 | Biological Process | multicellular organism development | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0030154 | Biological Process | cell differentiation | Interproscan |
| GO:0050793 | Biological Process | regulation of developmental process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K02599 | NOTCH1; Notch 1 | - | Endocrine resistance | ko01522 | deepkoala |