Genomic Location: WHPX01000669.1:60847...81040
NR annotation: XP_031572987.1, ER degradation-enhancing alpha-mannosidase-like protein 3 [Actinia tenebrosa]
Species Actinia equina · all data for this species · gene families
EGACTEQ4350017556-PB in AEQUI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q6GQB9 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Xenopus laevis OX=8355 GN=edem3 PE=2 SV=2 |
| Q2HXL6 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Mus musculus OX=10090 GN=Edem3 PE=1 SV=2 |
| Q9BZQ6 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Homo sapiens OX=9606 GN=EDEM3 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004095 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01532 all species → | Glyco_hydro_47 | Glycosyl hydrolase family 47 | Repeat | Interproscan |
| PF02225 all species → | PA | PA domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001382 all species → | Family | Glycoside hydrolase family 47 | Interproscan |
| IPR003137 all species → | Domain | PA domain | Interproscan |
| IPR046450 all species → | Homologous_superfamily | PA domain superfamily | Interproscan |
| IPR036026 all species → | Homologous_superfamily | Seven-hairpin glycosidases | Interproscan |
| IPR012341 all species → | Homologous_superfamily | Six-hairpin glycosidase-like superfamily | Interproscan |
| IPR044674 all species → | Family | ER degradation-enhancing alpha-mannosidase-like protein 1/2/3 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45679 all species → | ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004571 all species → | Molecular Function | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0005975 all species → | Biological Process | carbohydrate metabolic process | Interproscan |
| GO:0004559 all species → | Molecular Function | alpha-mannosidase activity | Interproscan |
| GO:0005783 all species → | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:1904380 all species → | Biological Process | endoplasmic reticulum mannose trimming | Interproscan |
| GO:1904382 all species → | Biological Process | mannose trimming involved in glycoprotein ERAD pathway | Interproscan |
EGACTEQ4350017556-PB.Genes whose expression across the transcriptome samples of Actinia equina tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia equina, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
