Genomic Location: WHPX01001349.1:605270...623138
NR annotation: XP_031556889.1, GATOR complex protein DEPDC5-like [Actinia tenebrosa]
| CDS | |||||
| EGACTEQ4350022051-PA | |||||
| Transcript |
| EGACTEQ4350022051-PA |
| Protein |
| EGACTEQ4350022051-PA |
| Uniprot term | Description |
|---|---|
| O75140 | GATOR1 complex protein DEPDC5 OS=Homo sapiens OX=9606 GN=DEPDC5 PE=1 SV=2 |
| P61460 | GATOR1 complex protein DEPDC5 OS=Mus musculus OX=10090 GN=Depdc5 PE=1 SV=2 |
| Q9W0E3 | GATOR complex protein Iml1 OS=Drosophila melanogaster OX=7227 GN=Iml1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF19418 | DEPDC5_CTD | DEPDC5 protein C-terminal region | Family | Interproscan |
| PF12257 | IML1 | Vacuolar membrane-associated protein Iml1 | Family | Interproscan |
| PF00610 | DEP | Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000591 | Domain | DEP domain | Interproscan |
| IPR036388 | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR045838 | Domain | DEPDC5, C-terminal | Interproscan |
| IPR048255 | Domain | Vacuolar membrane-associated protein Iml1, N-terminal domain | Interproscan |
| IPR027244 | Family | Vacuolar membrane-associated protein Iml1 | Interproscan |
| IPR036390 | Homologous_superfamily | Winged helix DNA-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13179 | DEP DOMAIN CONTAINING PROTEIN 5 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| GO:0005096 | Molecular Function | GTPase activator activity | Interproscan |
| GO:0005765 | Cellular Component | lysosomal membrane | Interproscan |
| GO:0010508 | Biological Process | positive regulation of autophagy | Interproscan |
| GO:0034198 | Biological Process | cellular response to amino acid starvation | Interproscan |
| GO:1904262 | Biological Process | negative regulation of TORC1 signaling | Interproscan |
| GO:1990130 | Cellular Component | GATOR1 complex | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K20404 | DEPDC5, SEA1; SEA/GATOR complex protein SEA1/DEPDC5 | - | Membrane trafficking | ko04131 | deepkoala |