Genomic Location: WHPX01000103.1:106091...116658
NR annotation: XP_031549158.1, NAD-dependent protein deacetylase sirtuin-1-like [Actinia tenebrosa]
| CDS | ||||
| EGACTEQ4350024673-PA | ||||
| Transcript |
| EGACTEQ4350024673-PA |
| Protein |
| EGACTEQ4350024673-PA |
| Uniprot term | Description |
|---|---|
| Q923E4 | NAD-dependent protein deacetylase sirtuin-1 OS=Mus musculus OX=10090 GN=Sirt1 PE=1 SV=2 |
| Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 OS=Homo sapiens OX=9606 GN=SIRT1 PE=1 SV=2 |
| A0A0G2JZ79 | NAD-dependent protein deacetylase sirtuin-1 OS=Rattus norvegicus OX=10116 GN=Sirt1 PE=3 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02146 | SIR2 | Sir2 family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR026591 | Homologous_superfamily | Sirtuin, catalytic core small domain superfamily | Interproscan |
| IPR003000 | Family | Sirtuin family | Interproscan |
| IPR029035 | Homologous_superfamily | DHS-like NAD/FAD-binding domain superfamily | Interproscan |
| IPR026590 | Domain | Sirtuin family, catalytic core domain | Interproscan |
| IPR050134 | Family | NAD-dependent sirtuin protein deacylases | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11085 | NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0070403 | Molecular Function | NAD+ binding | Interproscan |
| GO:0002039 | Molecular Function | p53 binding | Interproscan |
| GO:0003714 | Molecular Function | transcription corepressor activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005637 | Cellular Component | nuclear inner membrane | Interproscan |
| GO:0005654 | Cellular Component | nucleoplasm | Interproscan |
| GO:0017136 | Molecular Function | histone deacetylase activity, NAD-dependent | Interproscan |
| GO:0033553 | Cellular Component | rDNA heterochromatin | Interproscan |
| GO:0045892 | Biological Process | negative regulation of DNA-templated transcription | Interproscan |
| GO:0070932 | Biological Process | obsolete histone H3 deacetylation | Interproscan |