Detailed information of EGACTEQ4350027792-PD in Actinia equina

Genomic Location: WHPX01000556.1:268182...284060
NR annotation: XP_031549791.1, probable 3',5'-cyclic phosphodiesterase pde-5 isoform X3 [Actinia tenebrosa]
Species Actinia equina · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
No sequence record for EGACTEQ4350027792-PD in AEQUI (the gene ID may belong to a different isoform naming scheme). Try the gene search.
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P91119Probable 3',5'-cyclic phosphodiesterase pde-5 OS=Caenorhabditis elegans OX=6239 GN=pde-5 PE=3 SV=3
Q8CA95cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Mus musculus OX=10090 GN=Pde10a PE=1 SV=2
Q9Y233cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens OX=9606 GN=PDE10A PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001538 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01590
all species →		GAFGAF domainDomainInterproscan
PF00233
all species →		PDEase_I3'5'-cyclic nucleotide phosphodiesteraseDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR002073
all species →		Domain3'5'-cyclic nucleotide phosphodiesterase, catalytic domainInterproscan
IPR036971
all species →		Homologous_superfamily3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyInterproscan
IPR029016
all species →		Homologous_superfamilyGAF-like domain superfamilyInterproscan
IPR023088
all species →		Family3'5'-cyclic nucleotide phosphodiesteraseInterproscan
IPR003018
all species →		DomainGAF domainInterproscan
IPR003607
all species →		DomainHD/PDEase domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11347
all species →		CYCLIC NUCLEOTIDE PHOSPHODIESTERASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004114
all species →		Molecular Function3',5'-cyclic-nucleotide phosphodiesterase activityInterproscan
GO:0007165
all species →		Biological Processsignal transductionInterproscan
GO:0004118
all species →		Molecular Function3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activityInterproscan
GO:0010754
all species →		Biological Processnegative regulation of cGMP-mediated signalingInterproscan
GO:0008081
all species →		Molecular Functionphosphoric diester hydrolase activityInterproscan
GO:0005515
all species →		Molecular Functionprotein bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K18438PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10EC:3.1.4.17
EC:3.1.4.35
Morphine addictionko05032deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia equina tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia equina, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.not in the sequence tableopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.not in the sequence tableopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix–
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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