Gene detail

Detailed information of EGACTEQ4350033181-PA in Actinia equina

Genomic Location: WHPX01001432.1:936917...952789
NR annotation: XP_031559929.1, E3 ubiquitin-protein ligase MIB1-like [Actinia tenebrosa]
Species Actinia equina · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

EGACTEQ4350033181-PA

atgaTGGACCTTGTAGGCTACCGTGTTGTACGAGGGCCTGACTGGAAGTGGGGAAAGCAGGATGGAGGCGAAGGTCATGTGGGAACGGTGAGAAACTTTGAGAGCAACCAAGAAGTTGTGGTTGTTTGGGACAATGGTACTGCCGCCAACTATCGATGCTCTGGTGTTTATGACTTAAGGATCTTAGACAGCAGTCCAACAGGCATTAAACATGATGGGACTATGTGCGATGGATGTCGTATGCAGCCTATTTTTGGGTTAAGGTGGAAGTGTGCTGAATGTAACAATTATGACCTCTGTTCTCTATGTTACCATGGTGACAAGCATCAGCTTAGACATCGATTTTACAGGATCAGTCAACCAGGTGCAGAAAGaattcTTGTTGAAGCTAGAAGAAAGAGCAAAAAGATCACAGCGCGTGGGATATACCCTGGTGCTCGGGTTGTTAGAGGAGTAGACTGGCAATGGGAAGACCAGGATGGTGGTCCTGGTCGACGTGGTAAAGTTACAGAGCTCCAAGATTGGAGTGCCAACAGTCCTCGTAGTGCGGCATACATCATCTGGGATAATGGAGCAAAGAATCTTTATAGGGTTGGCTTTGAAGGGATGTCTGATCTGAAGGTCATTAGTGATGGCAAAGGAGGTTCATTGTACAGGGATCATCTACCATTACTTGGTGATAACAGACCAGGAAGCCAGACTGCCGCTCAAGGCCTACAAATTGGTGACCAGGTAACAGTTGACCTTGACCTTGAGATTGTCCAATCTCTACAGCATGGTCATGGTGGATGGACAGATGGCATGTATGAGacATTGACAACCGCAGGTACAGTTGTTGGTATTGATGAAGATCATGACATTGTGGTCCTTTATCCCAGTGGTAACAGATGGACATTCAACCCAGGTGTGTTGACCAAATCAAGTAGTTCAACCTCTACTGACAGCAGTGCTTCTTCTGCTGAGCCATCATTACAGCCATCAGTGTCAAACACATCAACAGGATCCTCTACCAGTCCATCGCCTTTTGCTGTGGGTGATCTGGTTCAAGTTAGTAGTGATATGGAACGAGTCAAGGTGTGGCAAAGAGGACATGGTGAATGGGCAGAGGCCATGATCCCTACTCTGGGTAAAATAGGACGAGTACAGCAAATCTACAATGACAATGACCTAAAGGTTGAGATCTGTGGAACCTCATGGACTTACAGTCCCTTGTGTGCAACCAAGGTAGCATCTCCTGGTGACTCTACATCCCTAGGGGAAGCTACAGGAGAGCGTCTATCGGTTCTCCTCAAGAAGCTATTTGAGACGCATGTGTCAGGTGATGCAGTAGAAGAACTGGTGAAGGCTGCTGCTAATGGAGACACGTCGAGCAGTGAAGAACTGATGAGCAAGACTGATGTAGATGCGAATGGTGTCTTTGCTGGTCATACTGCTCTCCAAGCTGCCAGTCAAAATGGACACGAAGACGTTGTTCGAGTTTTATTGCGTTACAAAGCTGATTTAGAAAAGGAGGACAAAGATGGCGATAGAGCCATCCATCATGCAGCTTTTGGTGACGAGTCTGGTGTTGTCGAGCAGTTAGTTCTTGCAGGAGCAGATATTAATGCCAGGAACAAGCGTCGCCAGTCTCCCTTACATGTGGCCGTTAACAAAGGCCATATATCTGTCGTAAAGTCACTATTAAAGCTCCATGCTCATCCTAGTTTACAGGACTCTGAGGGTGACACGCCGTTACACGACGCCATATCCAAGAAAAGAGATGATATGGTTACTATGCTACTAGAATCGAGTGCAGACGTTTCCATTgctaataataatggttttaaTTCTCTTCACCATGCTGCTTTGCGAGGAAATCCAAGCGCGATGCGAATACTGTTGGACAAGCTTCCTCGTCCTTGGATTGTCAACGAGAAGAAAGACGATGGTTATACAGCTTTACATCTGTCGTCACTCAATAACCACGTGGAAGTTGCTGAACTACTTGTCAAACAGGGCAAAGCTAACAAGGACGTACAGAATGGCAATCTACAAACACCTCTGCATTTGGCTGTGGAAAGACAACATACTCAAGTAGTTAGACTGCTTGTACGCGAGGGGTGTAAACTTGATATCCAAGACAAAGATGGAGATACTCCTCTTCACGAAGCATTGAGGCACCATACATTATCTCAGTTGCGACAGCTACAGGACATGCAAGATGTCGGCAAGTTATTAATGGGGTTAGGTACCCAGGGAACAGACAAGAAGAGTAGCGCATCAATAGCGCTGTTTCTCGCTGCTAATGGCGCCGACTTGACTATGAAGAACAGCAAAGGACAGACACCCCTGGACTTGTGCCCCGACCCCAATCTTTGTAAAGCACTTGCTAAGTGCCGCAAGGACAAGGGGATCGCCAAGAATCAATTGAACATATCTCAAACAGAAATCAACGAAGAAGCGTTACAAGAATGCGTGGTTTGTTCGGACAACAAGAGAGACACGCTGTTTGGACCGTGTTTCCACGTGACTACATGTTCACTGTGCTCTCCACGGGTAAAGAAATGTCTGATGTGTAAAGAACCAGTGCAATCAAGGACCAAGATCGAAGAGTGTATGGTTTGTTCAGAGAGGAAGGCCAATCTTTTATTCAAACCTTGTGGACATATATCTGCATGTGAAGTCTGCGGTTCTCTGATGAAAAAGTGTATCCAGTGCCGTGAAGACATCGAAGAGATGGTGCCGTTTATCGTCTGCTGTGGAGGAAAAGCTCCTTTACCGTTGTCCGAAAAAGCGTCCAACAAACAAGAGATCAGCACACAAGATCTGACACAGTTACAGCAACAGCTGCAAGATATGAAAGAACAGACCATGTGTCCAGTATGCATGGACAGACGAAAGAACCTGATATTCCTGTGTGGACACGGCACGTGCCAGCTGTGTGGAGACAGGATGCAAGAATGTCCAATGTGTAGAAAACCGGTGGAAAGACGGATTCTACTCTTTTAA

Transcript

EGACTEQ4350033181-PA

GTGCTAAACTAAATGAGATTGAGTAAAAAAGATTTTCGATTTTGGAATACCGGAAGTAAAGAACTAACCGGAAGTAGATTGTATTTCGTAACCATTCCCCTATGCAGAGAGTtgcaagaaagaaggaagagatTGTCAAACATGGCGACATGAAAGTTGAGACAAATTTTAGTTCAAAAATCTCcattttctctgtttttttgtctttatgaTGGACCTTGTAGGCTACCGTGTTGTACGAGGGCCTGACTGGAAGTGGGGAAAGCAGGATGGAGGCGAAGGTCATGTGGGAACGGTGAGAAACTTTGAGAGCAACCAAGAAGTTGTGGTTGTTTGGGACAATGGTACTGCCGCCAACTATCGATGCTCTGGTGTTTATGACTTAAGGATCTTAGACAGCAGTCCAACAGGCATTAAACATGATGGGACTATGTGCGATGGATGTCGTATGCAGCCTATTTTTGGGTTAAGGTGGAAGTGTGCTGAATGTAACAATTATGACCTCTGTTCTCTATGTTACCATGGTGACAAGCATCAGCTTAGACATCGATTTTACAGGATCAGTCAACCAGGTGCAGAAAGaattcTTGTTGAAGCTAGAAGAAAGAGCAAAAAGATCACAGCGCGTGGGATATACCCTGGTGCTCGGGTTGTTAGAGGAGTAGACTGGCAATGGGAAGACCAGGATGGTGGTCCTGGTCGACGTGGTAAAGTTACAGAGCTCCAAGATTGGAGTGCCAACAGTCCTCGTAGTGCGGCATACATCATCTGGGATAATGGAGCAAAGAATCTTTATAGGGTTGGCTTTGAAGGGATGTCTGATCTGAAGGTCATTAGTGATGGCAAAGGAGGTTCATTGTACAGGGATCATCTACCATTACTTGGTGATAACAGACCAGGAAGCCAGACTGCCGCTCAAGGCCTACAAATTGGTGACCAGGTAACAGTTGACCTTGACCTTGAGATTGTCCAATCTCTACAGCATGGTCATGGTGGATGGACAGATGGCATGTATGAGacATTGACAACCGCAGGTACAGTTGTTGGTATTGATGAAGATCATGACATTGTGGTCCTTTATCCCAGTGGTAACAGATGGACATTCAACCCAGGTGTGTTGACCAAATCAAGTAGTTCAACCTCTACTGACAGCAGTGCTTCTTCTGCTGAGCCATCATTACAGCCATCAGTGTCAAACACATCAACAGGATCCTCTACCAGTCCATCGCCTTTTGCTGTGGGTGATCTGGTTCAAGTTAGTAGTGATATGGAACGAGTCAAGGTGTGGCAAAGAGGACATGGTGAATGGGCAGAGGCCATGATCCCTACTCTGGGTAAAATAGGACGAGTACAGCAAATCTACAATGACAATGACCTAAAGGTTGAGATCTGTGGAACCTCATGGACTTACAGTCCCTTGTGTGCAACCAAGGTAGCATCTCCTGGTGACTCTACATCCCTAGGGGAAGCTACAGGAGAGCGTCTATCGGTTCTCCTCAAGAAGCTATTTGAGACGCATGTGTCAGGTGATGCAGTAGAAGAACTGGTGAAGGCTGCTGCTAATGGAGACACGTCGAGCAGTGAAGAACTGATGAGCAAGACTGATGTAGATGCGAATGGTGTCTTTGCTGGTCATACTGCTCTCCAAGCTGCCAGTCAAAATGGACACGAAGACGTTGTTCGAGTTTTATTGCGTTACAAAGCTGATTTAGAAAAGGAGGACAAAGATGGCGATAGAGCCATCCATCATGCAGCTTTTGGTGACGAGTCTGGTGTTGTCGAGCAGTTAGTTCTTGCAGGAGCAGATATTAATGCCAGGAACAAGCGTCGCCAGTCTCCCTTACATGTGGCCGTTAACAAAGGCCATATATCTGTCGTAAAGTCACTATTAAAGCTCCATGCTCATCCTAGTTTACAGGACTCTGAGGGTGACACGCCGTTACACGACGCCATATCCAAGAAAAGAGATGATATGGTTACTATGCTACTAGAATCGAGTGCAGACGTTTCCATTgctaataataatggttttaaTTCTCTTCACCATGCTGCTTTGCGAGGAAATCCAAGCGCGATGCGAATACTGTTGGACAAGCTTCCTCGTCCTTGGATTGTCAACGAGAAGAAAGACGATGGTTATACAGCTTTACATCTGTCGTCACTCAATAACCACGTGGAAGTTGCTGAACTACTTGTCAAACAGGGCAAAGCTAACAAGGACGTACAGAATGGCAATCTACAAACACCTCTGCATTTGGCTGTGGAAAGACAACATACTCAAGTAGTTAGACTGCTTGTACGCGAGGGGTGTAAACTTGATATCCAAGACAAAGATGGAGATACTCCTCTTCACGAAGCATTGAGGCACCATACATTATCTCAGTTGCGACAGCTACAGGACATGCAAGATGTCGGCAAGTTATTAATGGGGTTAGGTACCCAGGGAACAGACAAGAAGAGTAGCGCATCAATAGCGCTGTTTCTCGCTGCTAATGGCGCCGACTTGACTATGAAGAACAGCAAAGGACAGACACCCCTGGACTTGTGCCCCGACCCCAATCTTTGTAAAGCACTTGCTAAGTGCCGCAAGGACAAGGGGATCGCCAAGAATCAATTGAACATATCTCAAACAGAAATCAACGAAGAAGCGTTACAAGAATGCGTGGTTTGTTCGGACAACAAGAGAGACACGCTGTTTGGACCGTGTTTCCACGTGACTACATGTTCACTGTGCTCTCCACGGGTAAAGAAATGTCTGATGTGTAAAGAACCAGTGCAATCAAGGACCAAGATCGAAGAGTGTATGGTTTGTTCAGAGAGGAAGGCCAATCTTTTATTCAAACCTTGTGGACATATATCTGCATGTGAAGTCTGCGGTTCTCTGATGAAAAAGTGTATCCAGTGCCGTGAAGACATCGAAGAGATGGTGCCGTTTATCGTCTGCTGTGGAGGAAAAGCTCCTTTACCGTTGTCCGAAAAAGCGTCCAACAAACAAGAGATCAGCACACAAGATCTGACACAGTTACAGCAACAGCTGCAAGATATGAAAGAACAGACCATGTGTCCAGTATGCATGGACAGACGAAAGAACCTGATATTCCTGTGTGGACACGGCACGTGCCAGCTGTGTGGAGACAGGATGCAAGAATGTCCAATGTGTAGAAAACCGGTGGAAAGACGGATTCTACTCTTTTAACCGGCCACGAAATGTT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q86YT6	E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens OX=9606 GN=MIB1 PE=1 SV=1
Q80SY4	E3 ubiquitin-protein ligase MIB1 OS=Mus musculus OX=10090 GN=Mib1 PE=1 SV=1
Q6GNY1	E3 ubiquitin-protein ligase mib1 OS=Xenopus laevis OX=8355 GN=mib1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000493 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00023 all species →	Ank	Ankyrin repeat	Repeat	Interproscan
PF18346 all species →	SH3_15	Mind bomb SH3 repeat domain	Domain	Interproscan
PF12796 all species →	Ank_2	Ankyrin repeats (3 copies)	Repeat	Interproscan
PF00569 all species →	ZZ	Zinc finger, ZZ type	Domain	Interproscan
PF06701 all species →	MIB_HERC2	Mib_herc2	Domain	Interproscan
PF13920 all species →	zf-C3HC4_3	Zinc finger, C3HC4 type (RING finger)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002110 all species →	Repeat	Ankyrin repeat	Interproscan
IPR001841 all species →	Domain	Zinc finger, RING-type	Interproscan
IPR037252 all species →	Homologous_superfamily	Mib/herc2 domain superfamily	Interproscan
IPR036770 all species →	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	Interproscan
IPR013083 all species →	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan
IPR040847 all species →	Domain	Mind bomb, SH3 repeat domain	Interproscan
IPR043145 all species →	Homologous_superfamily	Zinc finger, ZZ-type superfamily	Interproscan
IPR000433 all species →	Domain	Zinc finger, ZZ-type	Interproscan
IPR010606 all species →	Domain	Mib-herc2	Interproscan
IPR042056 all species →	Domain	E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24202 all species →	E3 UBIQUITIN-PROTEIN LIGASE MIB2	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0004842 all species →	Molecular Function	ubiquitin-protein transferase activity	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0016567 all species →	Biological Process	protein ubiquitination	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006897 all species →	Biological Process	endocytosis	Interproscan
GO:0007219 all species →	Biological Process	Notch signaling pathway	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10645	MIB; E3 ubiquitin-protein ligase mind-bomb	EC:2.3.2.27	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia equina tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia equina, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →