Genomic Location: WHPX01000914.1:608566...613263
NR annotation: XP_031560114.1, mothers against decapentaplegic homolog 3-like [Actinia tenebrosa]
Species Actinia equina · all data for this species · gene families
EGACTEQ4350051959-PB in AEQUI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q9I9P9 | Mothers against decapentaplegic homolog 2 OS=Danio rerio OX=7955 GN=smad2 PE=2 SV=1 |
| Q15796 | Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 |
| Q62432 | Mothers against decapentaplegic homolog 2 OS=Mus musculus OX=10090 GN=Smad2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001605 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03166 all species → | MH2 | MH2 domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001132 all species → | Domain | SMAD domain, Dwarfin-type | Interproscan |
| IPR017855 all species → | Homologous_superfamily | SMAD-like domain superfamily | Interproscan |
| IPR008984 all species → | Homologous_superfamily | SMAD/FHA domain superfamily | Interproscan |
| IPR013790 all species → | Family | Dwarfin | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13703 all species → | SMAD | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006355 all species → | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0000978 all species → | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 all species → | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0006357 all species → | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0007179 all species → | Biological Process | transforming growth factor beta receptor signaling pathway | Interproscan |
| GO:0009653 all species → | Biological Process | anatomical structure morphogenesis | Interproscan |
| GO:0030154 all species → | Biological Process | cell differentiation | Interproscan |
| GO:0032924 all species → | Biological Process | activin receptor signaling pathway | Interproscan |
| GO:0045944 all species → | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| GO:0060395 all species → | Biological Process | SMAD protein signal transduction | Interproscan |
| GO:0070411 all species → | Molecular Function | I-SMAD binding | Interproscan |
| GO:0071144 all species → | Cellular Component | heteromeric SMAD protein complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K04500 | SMAD2; mothers against decapentaplegic homolog 2 | - | AGE-RAGE signaling pathway in diabetic complications | ko04933 | deepkoala |
Genes whose expression across the transcriptome samples of Actinia equina tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia equina, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
