Genomic Location: :...
NR annotation: CAB3984727.1, ER degradation-enhancing alpha-mannosidase 3 isoform X1 [Paramuricea clavata]
| CDS | |||||
| ENSAPQT00000001714 | |||||
| Transcript |
| ENSAPQT00000001714 |
| Protein |
| ENSAPQP00000001480.1 |
| Uniprot term | Description |
|---|---|
| Q6GQB9 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Xenopus laevis OX=8355 GN=edem3 PE=2 SV=2 |
| Q2HXL6 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Mus musculus OX=10090 GN=Edem3 PE=1 SV=2 |
| Q9BZQ6 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Homo sapiens OX=9606 GN=EDEM3 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01532 | Glyco_hydro_47 | Glycosyl hydrolase family 47 | Repeat | Interproscan |
| PF02225 | PA | PA domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR046450 | Homologous_superfamily | PA domain superfamily | Interproscan |
| IPR044674 | Family | ER degradation-enhancing alpha-mannosidase-like protein 1/2/3 | Interproscan |
| IPR001382 | Family | Glycoside hydrolase family 47 | Interproscan |
| IPR036026 | Homologous_superfamily | Seven-hairpin glycosidases | Interproscan |
| IPR003137 | Domain | PA domain | Interproscan |
| IPR012341 | Homologous_superfamily | Six-hairpin glycosidase-like superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45679 | ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004559 | Molecular Function | alpha-mannosidase activity | Interproscan |
| GO:0004571 | Molecular Function | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | Interproscan |
| GO:0005783 | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:1904380 | Biological Process | endoplasmic reticulum mannose trimming | Interproscan |
| GO:1904382 | Biological Process | mannose trimming involved in glycoprotein ERAD pathway | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0005975 | Biological Process | carbohydrate metabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10086 | EDEM3; ER degradation enhancer, mannosidase alpha-like 3 | - | Lectins | ko04091 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
© 2026 All Rights Reserved.
