Genomic Location: :...
NR annotation: CAB3991230.1, folylpolyglutamate synthase, mitochondrial-like isoform X1, partial [Paramuricea clavata]
| CDS | |||||
| ENSAPQT00000005079 | |||||
| Transcript |
| ENSAPQT00000005079 |
| Protein |
| ENSAPQP00000004422.1 |
| Uniprot term | Description |
|---|---|
| Q05932 | Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=FPGS PE=1 SV=3 |
| A6H751 | Folylpolyglutamate synthase, mitochondrial OS=Bos taurus OX=9913 GN=FPGS PE=2 SV=1 |
| Q924L9 | Folylpolyglutamate synthase, mitochondrial OS=Cricetulus griseus OX=10029 GN=FPGS PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02875 | Mur_ligase_C | Mur ligase family, glutamate ligase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036615 | Homologous_superfamily | Mur ligase, C-terminal domain superfamily | Interproscan |
| IPR004101 | Domain | Mur ligase, C-terminal | Interproscan |
| IPR018109 | Conserved_site | Folylpolyglutamate synthetase, conserved site | Interproscan |
| IPR036565 | Homologous_superfamily | Mur-like, catalytic domain superfamily | Interproscan |
| IPR001645 | Family | Folylpolyglutamate synthetase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11136 | FOLYLPOLYGLUTAMATE SYNTHASE-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0009058 | Biological Process | biosynthetic process | Interproscan |
| GO:0016881 | Molecular Function | acid-amino acid ligase activity | Interproscan |
| GO:0004326 | Molecular Function | tetrahydrofolylpolyglutamate synthase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0009396 | Biological Process | folic acid-containing compound biosynthetic process | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0046901 | Biological Process | tetrahydrofolylpolyglutamate biosynthetic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01930 | FPGS; folylpolyglutamate synthase | EC:6.3.2.17 | Antifolate resistance | ko01523 | deepkoala |