Gene detail

Detailed information of ENSAPQP00000011762.1 in Leptogorgia sarmentosa

Genomic Location: not available for this species
NR annotation: CAB3992322.1, methyl- -binding domain 2 [Paramuricea clavata]
Species Leptogorgia sarmentosa · all data for this species · gene families

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9UBB5	Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1
Q9Z2E1	Methyl-CpG-binding domain protein 2 OS=Mus musculus OX=10090 GN=Mbd2 PE=1 SV=2
Q9Z2D8	Methyl-CpG-binding domain protein 3 OS=Mus musculus OX=10090 GN=Mbd3 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007431 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16564 all species →	MBDa	p55-binding region of Methyl-CpG-binding domain proteins MBD	Domain	Interproscan
PF01429 all species →	MBD	Methyl-CpG binding domain	Domain	Interproscan
PF14048 all species →	MBD_C	C-terminal domain of methyl-CpG binding protein 2 and 3	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001739 all species →	Domain	Methyl-CpG DNA binding	Interproscan
IPR032343 all species →	Domain	Methyl-CpG-binding domain protein 2/3, p55-binding region	Interproscan
IPR025884 all species →	Domain	Methyl-CpG binding protein 2/3, C-terminal domain	Interproscan
IPR016177 all species →	Homologous_superfamily	DNA-binding domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12396 all species →	METHYL-CPG BINDING PROTEIN, MBD	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0000122 all species →	Biological Process	negative regulation of transcription by RNA polymerase II	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006346 all species →	Biological Process	DNA methylation-dependent constitutive heterochromatin formation	Interproscan
GO:0008327 all species →	Molecular Function	methyl-CpG binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11590	MBD2; methyl-CpG-binding domain protein 2	-	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.