Genomic Location: not available for this species
NR annotation: XP_028401303.1, rho guanine nucleotide exchange factor 12-like isoform X1 [Dendronephthya gigantea]
Species abbreviation LSARM · all data for this species · gene families
| CDS |
| ENSAPQT00000027900 |
| Transcript |
| ENSAPQT00000027900 |
| Protein |
| ENSAPQP00000025065.1 |
| UniProt accession | Description |
|---|---|
| Q9NZN5 | Rho guanine nucleotide exchange factor 12 OS=Homo sapiens OX=9606 GN=ARHGEF12 PE=1 SV=1 |
| Q8R4H2 | Rho guanine nucleotide exchange factor 12 OS=Mus musculus OX=10090 GN=Arhgef12 PE=1 SV=2 |
| O15085 | Rho guanine nucleotide exchange factor 11 OS=Homo sapiens OX=9606 GN=ARHGEF11 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001658 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF17838 all species → | PH_16 | PH domain | Domain | Interproscan |
| PF09128 all species → | RGS-like | Regulator of G protein signalling-like domain | Domain | Interproscan |
| PF00595 all species → | PDZ | PDZ domain | Domain | Interproscan |
| PF00130 all species → | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | Domain | Interproscan |
| PF00621 all species → | RhoGEF | RhoGEF domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000219 all species → | Domain | Dbl homology (DH) domain | Interproscan |
| IPR036034 all species → | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR001478 all species → | Domain | PDZ domain | Interproscan |
| IPR044926 all species → | Homologous_superfamily | RGS, subdomain 2 | Interproscan |
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| IPR041020 all species → | Domain | ARHGEF1-like, PH domain | Interproscan |
| IPR015212 all species → | Domain | Regulator of G protein signalling-like domain | Interproscan |
| IPR035899 all species → | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR036305 all species → | Homologous_superfamily | RGS domain superfamily | Interproscan |
| IPR046349 all species → | Homologous_superfamily | C1-like domain superfamily | Interproscan |
| IPR002219 all species → | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45872 all species → | RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0001664 all species → | Molecular Function | G protein-coupled receptor binding | Interproscan |
| GO:0007186 all species → | Biological Process | G protein-coupled receptor signaling pathway | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K07532 | ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12 | - | Membrane trafficking | ko04131 | deepkoala |
