Gene detail

Detailed information of ENSAPQP00000028522.1 in Leptogorgia sarmentosa

Genomic Location: not available for this species
NR annotation: XP_028401298.1, double-strand break repair protein MRE11-like isoform X1 [Dendronephthya gigantea]
Species Leptogorgia sarmentosa · all data for this species · gene families

Sequence

CDS

ENSAPQT00000031924

ATGGAGAACAGTGCAAGTCAATCAAGTGAAAGGtcaaatgatgatgaagatctTGATCATGAAAATACAATGTCCATTCTTATTGCGACCGATAATCACATCGGATTTATGGAGAAAGATCCAGAGAGAAGATCAGATTCGTTAGTAACctttgaagaaatattacaACTTGCGCAAGAGAAAAAGGTTGATTTTATTTTGCTCGGCGGTGATTTGTTCCACGAGAATAAGCCATCACGGAAAATAGTTCACAAGACAATGGAGATGATACGAAAGTATTGTATGGGAGATAAACCATGTTACCTGGAGTTTCTCAGTGATCAGTCCATCAATTTCGCTGCTAACAGTTTTCCCACGGTGAACTACGAAGATCCCAACTACAACATTTCCATTCCCATCTTTTCGATTCATGGCAATCATGATGATCCTGCAGGGGATGGCAATTTATGTACACTGAATCTATTTAGCGTCAGTGGGTTGGTAAATTATTTCGGCAAAGCATCCAACGTAGAAGATATTACCATAACTCCTATTCTTATGCAGAAAGGTGCGACAAAGCTAGCTTTATATGGACTAGGATCTGTACGGGATGAGCGTTTACATCGAACATTTCTTAATAAGAAAGTGAAAATGCTTCGTCCTAAAGAAGACGCGGATTCTTGGTTTAATTGCTTTGTTCTGCATCAAAATAGAGCTAAACATGGAGCAAAAAATCATATTCCGGAGAACTTTCTCGACGAGTTTCTTGACCTGGTAATCTGGGGTCATGAACATGAATGCCTGATTGATCCTCAGTACTCTGAGTGCGAGAAAGATATTTATATCAGTCAACCTGGATCATCAGTCGCAACATCGCTATGCGAGGGAGAAGCAAAACCGAAGTATGTTGGTATTCTAAGAATTGCTGGTAAGAATTTTCGAATGGATAAATTTCGTCTGAAGACCATCCGACCTTTCTACACGCGAGATGTGACATTGAGTGAAACTGATGTTGATCCCACTGATGATGCTGCTCAAAAGGAATATTTAACAGAACAGGTGGAAGAACTAATTGAATTATCTGAACGTGAACGTACCGGAGACAAAAGACAACCAAAACTGCCTTTGATAAGACTTCGGGTTGAGTACTCTGGTGGATTTTCGCCAATAAATGTCAATCGATTTGGGCAACAGTTTGTGAATCGTGTTGCAAATACGAAGgacattttaaatttctatCGAAAGCGAATTTCGACCATCAGAGATAAGAAAGGCAACGATGGTGGTACAGTTCGAATTCGTCCCGAAGTTTTGGACAATGGTCGTGTTGAGGATCTTGTCAATGAATATCTCAACTCGCAGGATAATAAATTGCAGTTGAGTGTTTTATCTGAGCGTAAGATGGGCCTGGCCTTACAAGAGTTTCTCGACAAAGACGAGCGAGAGGCAATAAAGGAGATCGTGAAATTACAACTCCACGACACTCAGAAAGCATTATCAACCAAGAACTTACGGGGCAAAGATATTGTTCAGGAAGTTGTTAAAGAAACTGAACGAAGTAGAACCGAGGAACTCAGTCAAGAGGAAGAGGCGAGGACGAGAAAGGCGTTACAAGAAGCAGTCCGACAGTCTGAAAGCAGAAGACAAGATGAACCAACAACTATCTCGTTTGACAGTGAAGACGAAAGTGAAAATGAGATCAGAACTACTACTAGAGGGAGAGGACGCGGCAGAGGGCGTGGCAGGGGCAAAGAACGAGGGCGAGGATCGCGGACAACTAGTAAACCACGAGACACGTCATCAGTTAGGACTGGTAACACATCGCGAgCTCCCGCTCGTGGAAGAAAACAACAGTCTCTGCAGTTTGAAAAAGGTGATGGGAGTTTATCTTTTGGCGAGAAAGAGTCGAGGGGAAACTCCTCTCGATCTGTGTATGATGAAAACTCGAATGATATAGATGAGGAAGAAGATCCCTTTGCTTTTCCGTCAAAACGAAAACGAAGATAA

Transcript

ENSAPQT00000031924

CTGTTCTCTGTAATTCTAAATTCCCATATGGTCTAGACGAATCGGTTAGCTGAAGACTTATCCAGCAGTCTTTACAAGCTTTGCCAGAAAAATTTTCTGTTTAAAAATCGATTTGCAATATGGCGGCCGCTTAGGCATGTGGCATACCCCCAGCAAGCATGCTAGGCGATTGTATCCCGAGACGAAGCCGAGAACGTTCCGAACCTTCCACAAACATCACCATCCAGTCAGTTTATAGATCAGTTTTCGCTCCAATATTGAAACAACCATGGAGAACAGTGCAAGTCAATCAAGTGAAAGGtcaaatgatgatgaagatctTGATCATGAAAATACAATGTCCATTCTTATTGCGACCGATAATCACATCGGATTTATGGAGAAAGATCCAGAGAGAAGATCAGATTCGTTAGTAACctttgaagaaatattacaACTTGCGCAAGAGAAAAAGGTTGATTTTATTTTGCTCGGCGGTGATTTGTTCCACGAGAATAAGCCATCACGGAAAATAGTTCACAAGACAATGGAGATGATACGAAAGTATTGTATGGGAGATAAACCATGTTACCTGGAGTTTCTCAGTGATCAGTCCATCAATTTCGCTGCTAACAGTTTTCCCACGGTGAACTACGAAGATCCCAACTACAACATTTCCATTCCCATCTTTTCGATTCATGGCAATCATGATGATCCTGCAGGGGATGGCAATTTATGTACACTGAATCTATTTAGCGTCAGTGGGTTGGTAAATTATTTCGGCAAAGCATCCAACGTAGAAGATATTACCATAACTCCTATTCTTATGCAGAAAGGTGCGACAAAGCTAGCTTTATATGGACTAGGATCTGTACGGGATGAGCGTTTACATCGAACATTTCTTAATAAGAAAGTGAAAATGCTTCGTCCTAAAGAAGACGCGGATTCTTGGTTTAATTGCTTTGTTCTGCATCAAAATAGAGCTAAACATGGAGCAAAAAATCATATTCCGGAGAACTTTCTCGACGAGTTTCTTGACCTGGTAATCTGGGGTCATGAACATGAATGCCTGATTGATCCTCAGTACTCTGAGTGCGAGAAAGATATTTATATCAGTCAACCTGGATCATCAGTCGCAACATCGCTATGCGAGGGAGAAGCAAAACCGAAGTATGTTGGTATTCTAAGAATTGCTGGTAAGAATTTTCGAATGGATAAATTTCGTCTGAAGACCATCCGACCTTTCTACACGCGAGATGTGACATTGAGTGAAACTGATGTTGATCCCACTGATGATGCTGCTCAAAAGGAATATTTAACAGAACAGGTGGAAGAACTAATTGAATTATCTGAACGTGAACGTACCGGAGACAAAAGACAACCAAAACTGCCTTTGATAAGACTTCGGGTTGAGTACTCTGGTGGATTTTCGCCAATAAATGTCAATCGATTTGGGCAACAGTTTGTGAATCGTGTTGCAAATACGAAGgacattttaaatttctatCGAAAGCGAATTTCGACCATCAGAGATAAGAAAGGCAACGATGGTGGTACAGTTCGAATTCGTCCCGAAGTTTTGGACAATGGTCGTGTTGAGGATCTTGTCAATGAATATCTCAACTCGCAGGATAATAAATTGCAGTTGAGTGTTTTATCTGAGCGTAAGATGGGCCTGGCCTTACAAGAGTTTCTCGACAAAGACGAGCGAGAGGCAATAAAGGAGATCGTGAAATTACAACTCCACGACACTCAGAAAGCATTATCAACCAAGAACTTACGGGGCAAAGATATTGTTCAGGAAGTTGTTAAAGAAACTGAACGAAGTAGAACCGAGGAACTCAGTCAAGAGGAAGAGGCGAGGACGAGAAAGGCGTTACAAGAAGCAGTCCGACAGTCTGAAAGCAGAAGACAAGATGAACCAACAACTATCTCGTTTGACAGTGAAGACGAAAGTGAAAATGAGATCAGAACTACTACTAGAGGGAGAGGACGCGGCAGAGGGCGTGGCAGGGGCAAAGAACGAGGGCGAGGATCGCGGACAACTAGTAAACCACGAGACACGTCATCAGTTAGGACTGGTAACACATCGCGAgCTCCCGCTCGTGGAAGAAAACAACAGTCTCTGCAGTTTGAAAAAGGTGATGGGAGTTTATCTTTTGGCGAGAAAGAGTCGAGGGGAAACTCCTCTCGATCTGTGTATGATGAAAACTCGAATGATATAGATGAGGAAGAAGATCCCTTTGCTTTTCCGTCAAAACGAAAACGAAGATAAGGGTTTTCAAGCAGCATACGTTGAGTTAAGTGGCGCTGGACACATGCGGTTCGTTTACAAAAGAGATGTTTTTTTACAACTGCGGAAAGCAGTCGCTGTTTTTAATGGCACACATGCAGGAGAAGAAACAGTGAACAAACTGGCAAGATATGAACCTCTGGCCATTTTCGAAAAACGTGGTAaacactgtttttttttcaacagttcAGCATTTCATGTTTCTGTAAGTGTACGTCAAGGGAGAAGGAGATAAGACCCCTGGGCAATCGAATCTAAAGGTCCTGTAAGCTCTGGAGGTAACTATAGAATACCCCGCCATGCATGTTCATTAGGCTAAATACGTCAAatgaacttcaaaatcattaaGTAAAATTGCTTCATTCCCAGTCATGTTGGGGTTCGAGTAAGGGTTTGGGTAAGCTTCCATTATTGCACTTTAagtttcaacaaaattcaaagaGTTTGTGAGTTTATTCTGATGTAAAAATACGAAGTCCAAATGTGCGGGGTATTCTATAGTTATTCCGCTCTGGACTCCATTGACTCACTGAAGTTACATCTGTCATGCGATAGCATCATGACACACACGATCATTTATCTGTTGTTAGCAAAAAAATGGCAATCTCGACCCATCGGCCTCTTTTGATTCGACTCGTACCCAGGCCCCGTACGCAACGtggaaatttgcatagcgtgcatgtgaaaaaaaccccaaaacaACTCTATCTCCTCCATCAATCAGATTGCAGTAGGCCCCGCCAAATAAATCGATTACGTCTACGATCGAAGGCAAATAGTCAAAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P49959	Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3
Q60HE6	Double-strand break repair protein MRE11 OS=Macaca fascicularis OX=9541 GN=MRE11 PE=2 SV=1
Q61216	Double-strand break repair protein MRE11 OS=Mus musculus OX=10090 GN=Mre11 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003776 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00149 all species →	Metallophos	Calcineurin-like phosphoesterase	Domain	Interproscan
PF04152 all species →	Mre11_DNA_bind	Mre11 DNA-binding presumed domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR004843 all species →	Domain	Calcineurin-like phosphoesterase domain, ApaH type	Interproscan
IPR029052 all species →	Homologous_superfamily	Metallo-dependent phosphatase-like	Interproscan
IPR038487 all species →	Homologous_superfamily	Mre11, capping domain	Interproscan
IPR003701 all species →	Family	DNA double-strand break repair protein Mre11	Interproscan
IPR041796 all species →	Domain	Mre11 nuclease, N-terminal metallophosphatase domain	Interproscan
IPR007281 all species →	Domain	Mre11, DNA-binding	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10139 all species →	DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000014 all species →	Molecular Function	single-stranded DNA endodeoxyribonuclease activity	Interproscan
GO:0000723 all species →	Biological Process	telomere maintenance	Interproscan
GO:0000724 all species →	Biological Process	double-strand break repair via homologous recombination	Interproscan
GO:0006303 all species →	Biological Process	double-strand break repair via nonhomologous end joining	Interproscan
GO:0007095 all species →	Biological Process	mitotic G2 DNA damage checkpoint signaling	Interproscan
GO:0030870 all species →	Cellular Component	Mre11 complex	Interproscan
GO:0031573 all species →	Biological Process	mitotic intra-S DNA damage checkpoint signaling	Interproscan
GO:0035861 all species →	Cellular Component	site of double-strand break	Interproscan
GO:0042138 all species →	Biological Process	meiotic DNA double-strand break formation	Interproscan
GO:0097552 all species →	Biological Process	mitochondrial double-strand break repair via homologous recombination	Interproscan
GO:0016787 all species →	Molecular Function	hydrolase activity	Interproscan
GO:0004520 all species →	Molecular Function	DNA endonuclease activity	Interproscan
GO:0006302 all species →	Biological Process	double-strand break repair	Interproscan
GO:0008296 all species →	Molecular Function	3'-5'-DNA exonuclease activity	Interproscan
GO:0004519 all species →	Molecular Function	endonuclease activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0030145 all species →	Molecular Function	manganese ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10865	MRE11; double-strand break repair protein MRE11	-	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.