Gene detail

Detailed information of ENSAVKP00000012754.1 in Catalaphyllia jardinei

Genomic Location: chr12:2722682...2749782
NR annotation: XP_020610001.1, nardilysin-like [Orbicella faveolata]
Species Catalaphyllia jardinei · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSAVKT00000013633

ATGGCGCCAATTGTGAAGTCGCCGAATGACCCCAGAGAGTACAGGTACAAATCGGCGTcttttcattcattcgttcctcttttttcttttatttcatggTCAAATTTATGCTTTAAAATTTCGAGAATGGTCAAATTAACTTCCAGTGGATCGTTGCAAAGAAAGTCCGGTCTATCAACCATTTACCGGCGTTTACCGCTGTCGGTCATACATTTAGAAAATGGTTTAACAGCACTGTTAGTATCAGATACACAATCAGTCACTCATCGCAAACACCATGACAGTGATATGTCGACAACAGATGATGAAGATGGGTGTAGTGAAGACCTTGATGACGAGagtgatgttgatgatgatgataacagtgatgatggtgatgatgacatTGATGGAATAAGGAGTGAAGATCCTGATATGGACCAAGGAAATGATTGTGAGAGGTTGAGAAAAGCAAAAGATACAAAACTATTAACGGATAGTTCACTTTTAACAGATAATTTCTTCTCTTTGAGCTGGGTATTTATGCACTGCAATTTTCACTGCTACAATTTAAgtaccctatctaaggatcaCACTGGGAACACTTGTGATTATGGacaaaatgataccctatttaaggatcaAGAGCCACAAAAATCTAACCTTATCCCTGTGGATCTTCAtcaaatttccattttttttcagtcTGCTGCAGCCCTTTGCATTGGTATTGGTAGCTTTTCTGATCCAGACAATGTTCCAGGATTAGCTCACTTCTTAGAACATATGGTTTTCATGGGCAGTGAAAAATACCCTGATGAGAATGCCTTTGATGCTTTTATCAAGAAACATGGAGGATCAGATAATGCTTCAACTGATTGTGAAAGGACCACCTTCACCTTTGATGTCAGACGGAAGTACTTCAGGGAAACTTTAGACAGGTTTGCACAGTTCTTCATTTCTCCTCTTCTTAAAGAAGACAGTGTTGACAGAGAAATACAGGCAGTGGAAAGTGAATTTAGAATGAGTTATCAGAGTGACTCTGTCAGGAAAATGCAGCTCCTTGCTTTACTGACTGAAAAAGGTCATCCATTTGGAAAATTTCTCTGGGGAAATGAAGAAACACTACAGAAAATTCCAAAGGAAAAGAATATCGATGTGAATAAATCTTTACAAGATTTTCAGAAGAGAATGTACTCTGCACAATACATGACACTAGCTGTGATTTCAAGAGagtctCTTGATGATTTGGAAAAGATGGTCCGagaatcattttctaaaattccCAATAAAGGGTCTCAAATGCTACTAacaatttcttgtatttttcattttgcagTGATACCAGTGAAGGATGTACATCAGCTAGAGATAACTTGGGTTCTACCGCCGCAGCTAAAGTATTACAGAATCAAGCCAATGCATTATGTATCCTGGTTAATGGGACACGAAGGACCAGGAAGTATTTTGTCACTGCTGATACAAAAATCCTGGGCTGCCAGTTTACTTTGTGGCAATGGAGAATCtggccaagaacacaacactagTTTTGCTCTCTTCCCCTGTTTGATTAGTCTTACAgATGAAGGCATAGATCACATTTTTGAGATTTTGACTATTGTGTTTCAATATCTGGAATTACTAAGACAGAAAGGACCACAGGAGAGAATATACAAGGAACTACAGACCATCGAGGAGAATGAGTTCAGATTTCGTGAACAGTGCGAGCCCTATGACTATGTCGAGGACCTTGTGGAAAACATGCAGCTATATCCTGAAGAAGATTATCTAACAGGAGATCAACTGATGTGGGAGTTTAATGAAGAGGTCATTCAGAATGTTCAAAACATGCTTACGCCAGAAAGGGCCAATATTTTGCTGTTGTCCAAGAGGTTCCAGGATGAATGTACGGATTATGAGCCTTGGTTCCAGACTCCCTACATTTGCTCTGATCTGGAATTGAACCCAGAACTCCATTTTCCTGAAGAAAATAAGTTCATTGGTAAGTTTTTGAGGtttccAGAACTAGTCCATGACTGCCATCTTGGGAAGGTCTGGCACTCAAAGGACACCAAATTCAAAACACCAAGAGGTTTGTCCttttatttgattttaatttttagcATGGTTCAATCCGACCTTTTCCTGAGTGTGTTGGAGTATAACTTGAAGGAAATCGCTTATGCTGCCGATGTAGCTCAGTTGGGTTATTCCATGACGGTCACCGAAACGGGAATTGTTCTTAAACTGGAAGGATTTAACCACAAATTAGCGCTGTTGTTTGAGACGATTATTGATCGCATGGCAAATTTTACTGTTAGTACTCAGACGTTTGAGATGGTCAAGCGTAAGTTGATGAGGTCATACCGTAACTCGATCATCAAGCCACAAAAGTTGGTCAGGTCTGTTCGCCTGTCTATCTTGCAACATGTCAAATGGACAACTGTTGACAAGCGGAGCGTCATTCCTGATGCCACAGTTGAGACTCTTCGACATTTTGTATCCTGTTTTAAGTCAAAGTTGTTTGTGGAAAGCTTGATTCAAGGAAATATCACTTCCCAGGTATACATACATTTTCCATTCAATCTTGTTTACAGTAAACTGCAGTTTATGCCACTCAGCAGTTGTCTTCGTCCTGAGatTCGAGTCATCCAGTTACCAGAAGGTGAAAGCATTTGCCGTGTCATGGGATTTAACAAAGACGATGATAACTCTGTCGTTACTAACTATTACCAGACGCAGGCTGGAAAATTCAGTGCTGAACATGTCGAGGGTCGGATTGACGCATTCTTAGATGAATTTGGAGAAATTTTACGTTCCCTATCAGACGAAGACTTCAAGAGCCagGTGGACTCACTTATTGAACTGAAGGAACACGAGGACCTTAGTTTGGCGGACGAAGCAGACAGAAACTGGAACGAAGTTTTGGATCAGACTTACATCTTCAACAGAAAACGACGAGAGGTGGAGAGCTTAAGAAAACTGAGCAAAGAAGATCTTTATCAGTGGTTCATGTCCCACAGGAAAAGTGGCGATAGACTCAAGAAGCTAAGTGTTCAGATCATTGGCTCAGGGCAGTGCGAGACTCGCGCCTGCGTAGACATGGCTGTAGACGCAGATAGTGGCTTGGGTAATGATGATGACTGGCAGATTCGTCCTGTTCTTGTTGACACTTCCGGTAGCCAAGTCCTTTGCATTAAGAACATTTCGGAGTTCAAAAGAACGAGAGCTATTTTCCCCGTGGTCAAAATTAAGTGA

Transcript

ENSAVKT00000013633

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8BHG1	Nardilysin OS=Mus musculus OX=10090 GN=Nrdc PE=1 SV=1
P47245	Nardilysin OS=Rattus norvegicus OX=10116 GN=Nrdc PE=1 SV=1
O43847	Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001147 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF05193 all species →	Peptidase_M16_C	Peptidase M16 inactive domain	Domain	Interproscan
PF16187 all species →	Peptidase_M16_M	Middle or third domain of peptidase_M16	Family	Interproscan
PF00675 all species →	Peptidase_M16	Insulinase (Peptidase family M16)	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR050626 all species →	Family	Peptidase M16	Interproscan
IPR011249 all species →	Homologous_superfamily	Metalloenzyme, LuxS/M16 peptidase-like	Interproscan
IPR007863 all species →	Domain	Peptidase M16, C-terminal	Interproscan
IPR001431 all species →	Binding_site	Peptidase M16, zinc-binding site	Interproscan
IPR032632 all species →	Domain	Peptidase M16, middle/third domain	Interproscan
IPR011765 all species →	Domain	Peptidase M16, N-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43690 all species →	NARDILYSIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0004222 all species →	Molecular Function	metalloendopeptidase activity	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01411	NRD1; nardilysin	EC:3.4.24.61	Peptidases and inhibitors	ko01002	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Catalaphyllia jardinei tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Catalaphyllia jardinei, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →