Detailed information of ENSAVKP00000014131.1 in Catalaphyllia jardinei

Genomic Location: chr13:9047546...9059109
NR annotation: XP_020605533.1, ADAM 17-like protease [Orbicella faveolata]
Species Catalaphyllia jardinei · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9Z1K9Disintegrin and metalloproteinase domain-containing protein 17 OS=Rattus norvegicus OX=10116 GN=Adam17 PE=1 SV=1
P78536Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ADAM17 PE=1 SV=1
Q9Z0F8Disintegrin and metalloproteinase domain-containing protein 17 OS=Mus musculus OX=10090 GN=Adam17 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000651 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF16698
all species →		ADAM17_MPDMembrane-proximal domain, switch, for ADAM17DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR032029
all species →		DomainADAM17, membrane-proximal domainInterproscan
IPR051489
all species →		FamilyDisintegrin and Metalloproteinase Domain-ContainingInterproscan
IPR036436
all species →		Homologous_superfamilyDisintegrin domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR45702
all species →		ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBERInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004222
all species →		Molecular Functionmetalloendopeptidase activityInterproscan
GO:0005886
all species →		Cellular Componentplasma membraneInterproscan
GO:0006509
all species →		Biological Processmembrane protein ectodomain proteolysisInterproscan
GO:0007219
all species →		Biological ProcessNotch signaling pathwayInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K05146TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9-CD moleculesko04090deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Catalaphyllia jardinei tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Catalaphyllia jardinei, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix–
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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