Detailed information of ENSBQFP00000006591.1 in Heliopora coerulea

Genomic Location: JASJOG010000001.1:254304...297080
NR annotation: XP_028408787.1, V-type proton ATPase 116 kDa subunit a-like isoform X1 [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q29466V-type proton ATPase 116 kDa subunit a 1 OS=Bos taurus OX=9913 GN=ATP6V0A1 PE=1 SV=1
Q9Z1G4V-type proton ATPase 116 kDa subunit a 1 OS=Mus musculus OX=10090 GN=Atp6v0a1 PE=1 SV=3
P25286V-type proton ATPase 116 kDa subunit a 1 OS=Rattus norvegicus OX=10116 GN=Atp6v0a1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001666 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01496
all species →
V_ATPase_IV-type ATPase 116kDa subunit family FamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR002490
all species →
FamilyV-type ATPase, V0 complex, 116kDa subunit familyInterproscan
IPR026028
all species →
FamilyATPase, V0 complex, subunit 116kDa, eukaryoticInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11629
all species →
VACUOLAR PROTON ATPASESInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0033179
all species →
Cellular Componentproton-transporting V-type ATPase, V0 domainInterproscan
GO:0046961
all species →
Molecular Functionproton-transporting ATPase activity, rotational mechanismInterproscan
GO:1902600
all species →
Biological Processproton transmembrane transportInterproscan
GO:0000220
all species →
Cellular Componentvacuolar proton-transporting V-type ATPase, V0 domainInterproscan
GO:0005886
all species →
Cellular Componentplasma membraneInterproscan
GO:0007035
all species →
Biological Processvacuolar acidificationInterproscan
GO:0016471
all species →
Cellular Componentvacuolar proton-transporting V-type ATPase complexInterproscan
GO:0051117
all species →
Molecular FunctionATPase bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K02154ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a-Exosomeko04147deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000006591.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
36TPM > 0
6Conditions
136.4Max TPM
66.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 17 58.97 86.38
polyp and skeleton · 31C, 3week 6 6 78.39 136.44
polyp and skeleton · 28C, 3week 6 6 86.22 122.51
polyp and skeleton · 26C, 3week 4 3 47.38 77.94
polyp and skeleton · 28C, 24hr 2 2 68.85 74.69
polyp and skeleton · 31C, 24hr 2 2 70.64 71.50

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 86.38
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 81.89
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 67.79
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 65.52
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 65.48
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 64.20
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 63.95
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 63.90
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 59.27
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 57.37
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 55.23
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 53.65
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 46.81
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 46.41
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 44.34
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 41.24
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 39.11
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 136.44
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 83.57
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 80.65
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 59.74
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 55.12
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 54.82
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 122.51
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 114.29
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 91.19
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 71.41
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 59.76
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 58.15
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 77.94
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 63.85
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 47.74
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 0.00
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 74.69
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 63.01
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 71.50
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 69.78

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated6ENSBQFP000000435680.787165768505609
Negatively correlated78ENSBQFP00000009242-0.694137129761705

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000006591, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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